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首页> 外文期刊>Psychological medicine >Systematic review of multi-symptom conditions in Gulf War veterans.
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Systematic review of multi-symptom conditions in Gulf War veterans.

机译：对海湾战争退伍军人中多症状状况的系统评价。

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BACKGROUND: Gulf War veterans have a number of health complaints. We therefore decided to carry out a systematic review to identify and summarize the findings from studies that have assessed multi-symptom conditions in Gulf War veterans and in an unexposed comparison group. METHOD: Studies published between January 1990 and May 2004 were identified by searching a large number of electronic databases. Reference lists and websites were also searched and key researchers were contacted. Studies were included if they compared the prevalence of chronic fatigue syndrome, multiple chemical sensitivity, CDC-defined chronic multi-symptom illness, fibromyalgia, or symptoms of either fatigue or numbness and tingling in Gulf War veterans and non-Gulf veterans. A total of 2401 abstracts were independently reviewed by two authors. RESULTS: Twenty-three publications fulfilled the inclusion criteria. Gulf deployment was most strongly associated with chronic fatigue syndrome (OR 3.8, 95% CI 2.2-6.7). Gulf War veterans were also approximately three and a half times more likely than non-Gulf veterans to report multiple chemical sensitivity or chronic multi-symptom illness as defined by CDC. The methodological quality of the studies varied but the later and larger studies were of a high methodological standard with robust sampling strategies, adequate response rates and good adjustment for confounders. CONCLUSIONS: The results support the hypothesis that deployment to the Gulf War is associated with greater reporting of multi-symptom conditions.
机译：背景：海湾战争退伍军人有许多健康问题。因此，我们决定进行系统的审查，以鉴定和总结来自评估海湾战争退伍军人和未暴露的比较组中多症状状态的研究结果。方法：通过搜索大量电子数据库来鉴定1990年1月至2004年5月之间发表的研究。还搜索了参考书目和网站，并联系了主要研究人员。如果他们比较了海湾战争退伍军人和非海湾退伍军人的慢性疲劳综合症，多种化学敏感性，CDC定义的慢性多症状疾病，纤维肌痛或疲劳或麻木和刺痛症状的患病率，则纳入研究。两位作者独立审查了总共2401个摘要。结果：23个出版物符合纳入标准。海湾部署与慢性疲劳综合症最相关（OR 3.8，95％CI 2.2-6.7）。海湾战争退伍军人报告CDC定义的多种化学敏感性或慢性多症状疾病的可能性也比非海湾退伍军人高大约三倍半。研究的方法学质量各不相同，但后来的和较大的研究具有较高的方法学标准，具有可靠的采样策略，足够的响应率和对混杂因素的良好调整。结论：结果支持这样的假设，即部署到海湾战争与更多的多症状疾病报告有关。

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