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首页> 外文期刊>Quality of Life Research >Health-related Quality of Life, Depression and Anxiety in Thyroid Cancer Patients
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Health-related Quality of Life, Depression and Anxiety in Thyroid Cancer Patients

机译：甲状腺癌患者与健康相关的生活质量，抑郁和焦虑

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摘要

Objectives: We examined the relationships among physical complaints, health-related quality of life (HRQL), anxiety and depression in differentiated thyroid cancer (DTC) patients under short-term hypothyroidism. Methods: We conducted a cross-sectional study in 136 patients hypothyroid on thyroid hormone withdrawal (THW) hospitalized for radioiodine administration. Patients were assessed using Short Form SF-36 (SF-36), Hospital Anxiety and Depression Scale (HADS), Profile of Mood States (POMS), Beck Depression Inventory (BDI), and physical complaints. Results: Compared to the German general population, hypothyroid patients had significantly impaired HRQL. Surprisingly, the prevalence of anxiety (62.5%), but not depression (17.9%) was much higher in hypothyroid DTC patients than in the general population. In multivariate analysis, depression and age were independently associated with the physical health score (R 2 = 0.21), but only psychological variables (depression, mood disturbance, and anxiety) were associated with the mental health score (R 2 = 0.43), on the SF-36 HRQL instrument. Conclusions: HRQL is severely impaired in DTC patients under short-term hypothyroidism. As potential predictors of generic HRQL impairment, depression, anxiety, and mood disturbance could be used to preselect the patients most needing psychiatric care. The high frequency of anxiety should be considered in the aftercare of thyroid cancer patients.
机译：目的：我们研究了短期甲状腺功能减退症下分化型甲状腺癌（DTC）患者的身体不适，健康相关生活质量（HRQL），焦虑和抑郁之间的关系。方法：我们对136例甲状腺功能减退的甲状腺功能减退患者进行了横断面研究。使用简短表格SF-36（SF-36），医院焦虑和抑郁量表（HADS），情绪状态档案（POMS），贝克抑郁量表（BDI）和身体不适进行评估。结果：与德国普通人群相比，甲状腺功能减退患者的HRQL明显受损。令人惊讶的是，甲状腺功能低下的DTC患者焦虑症的患病率（62.5％），而非抑郁症的患病率（17.9％）比普通人群要高得多。在多变量分析中，抑郁和年龄与身体健康评分独立相关（R 2 = 0.21），但只有心理变量（抑郁，情绪障碍和焦虑）与心理健康评分相关（R 2 < / sup> = 0.43），在SF-36 HRQL仪器上。结论：短期甲状腺功能减退的DTC患者HRQL严重受损。作为一般性HRQL障碍，抑郁症，焦虑症和情绪障碍的潜在预测指标，可以用来预选最需要精神病治疗的患者。甲状腺癌患者的术后护理应考虑高焦虑程度。

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  • 来源
    《Quality of Life Research》 |2006年第4期|695-703|共9页
  • 作者

    Sefik Tagay; Stephan Herpertz; Matthias Langkafel; Yesim Erim; Andreas Bockisch; Wolfgang Senf; Rainer Görges;

  • 作者单位

    Clinic of Psychosomatic Medicine and Psychotherapy University of Duisburg-Essen Virchowstr. 174 45147 Essen Germany;

    Department of Psychosomatic Medicine and Psychotherapy Ruhr-University Bochum Germany;

    Clinic of Psychosomatic Medicine and Psychotherapy University of Duisburg-Essen Virchowstr. 174 45147 Essen Germany;

    Clinic of Psychosomatic Medicine and Psychotherapy University of Duisburg-Essen Virchowstr. 174 45147 Essen Germany;

    Department of Nuclear Medicine University of Duisburg-Essen Essen Germany;

    Clinic of Psychosomatic Medicine and Psychotherapy University of Duisburg-Essen Virchowstr. 174 45147 Essen Germany;

    Department of Nuclear Medicine University of Duisburg-Essen Essen Germany;

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  • 正文语种 eng
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  • 关键词

    Differentiated thyroid cancer; Hypothyroidism; Health-related quality of life; Anxiety; Depression;

    机译：分化型甲状腺癌;甲状腺功能减退;健康相关生活质量;焦虑症;抑郁症;

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