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IMAGING DOSE OF HUMAN ORGANS FROM kV-CBCT IN IMAGE-GUIDED RADIATION THERAPY

机译:kV-CBCT影像引导放射治疗中人体器官的成像剂量

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摘要

This study investigates dose distribution due to kV cone-beam computed tomography (CBCT) for the patients undergoing CBCT-based image-guided radiation therapy (IGRT). The kV-CBCT provides an efficient image-guidance tool for acquiring the latest volumetric image of a patient's anatomy, and has been being routinely used in clinics for an accurate treatment setup. Imaging radiation doses resulting from six different acquisition protocols of the on-board imager (OBI) were calculated using a Geant4 Application for Tomographic Emission (GATE) Monte Carlo simulation toolkit, and the absorbed doses by various organs were analyzed for the adult and pediatric numerical XCAT phantoms in this study. The calculated organ doses range from 0.1 to 24.1 mGy in the adult phantom, and from 0.1 to 36.8 mGy in the pediatric one. The imaging organ doses to the pediatric phantom turn out to be consistently higher than those to the adult phantom. It is believed that our results would provide reliable data to the clinicians for their making better decisions on CBCT scanning options and would also provide a platform for developing a new kV-CBCT scanning protocol in conjunction with a low-dose capability.
机译:这项研究调查了接受基于CBCT的图像引导放射治疗(IGRT)的患者的kV锥形束计算机断层扫描(CBCT)引起的剂量分布。 kV-CBCT提供了一种有效的图像引导工具,可用于获取患者解剖结构的最新体积图像,并且已在临床中常规用于准确的治疗设置。使用Geant4断层扫描应用程序(GATE)蒙特卡罗模拟工具包计算了来自六种不同的车载成像仪(OBI)采集协议的成像辐射剂量,并分析了成人和儿科数值对各个器官的吸收剂量本研究中的XCAT幻像。在成人体模中,计算的器官剂量范围为0.1至24.1 mGy,在儿科模型中为0.1至36.8 mGy。事实证明,对儿童体模的成像器官剂量始终高于对成人体模的成像器官剂量。据信,我们的结果将为临床医生提供可靠的数据,以便他们对CBCT扫描选项做出更好的决策,还将为开发具有低剂量功能的新kV-CBCT扫描协议提供平台。

著录项

  • 来源
    《Radiation Protection Dosimetry》 |2017年第2期|194-200|共7页
  • 作者单位

    Department of Nuclear and Quantum engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea;

    Department of Radiation Oncology Yonsei Cancer Center, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea;

    Department of Nuclear and Quantum engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea;

    Department of Nuclear and Quantum engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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