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DEVELOPMENT AND CLINICAL APPLICATION OF A LENGTH-ADJUSTABLE WATER PHANTOM FOR TOTAL BODY IRRADIATION

机译：全身照射的可调节长度的幻影的开发及临床应用

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摘要

A new type of water phantom which would be specialised for the absorbed dose measurement in total body irradiation (TBI) treatment is developed. Ten millimetres of thick Plexiglas plates were arranged to form a square cube with 300 mm of edge length. An appropriate sleeve-type piston was installed on the side wall, and a tabular Plexiglas piston was positioned inside the sleeve. By pushing and pulling the piston, the length of the self-made water phantom could be varied to meet the required patients' physical sizes. To compare the international standard water phantom with the length-adjustable and the Plexiglas phantoms, absorbed dose for 6-MV X ray was measured by an ionisation chamber at different depths in three kinds of phantoms. In 70 cases with TBI, midplane doses were metered using the length-adjustable and the Plexiglas phantoms for simulating human dimensions, and dose validation was synchronously carried out. There were no significant statistical differences, p > 0.05, through statistical processing of data from the international standard water phantom and the self-designed one. There were significant statistical differences, p < 0.05, between the two sets of data from the standard and the Plexiglas one. In addition, the absolute difference had a positive correlation with the varied depth of the detector in the Plexiglas phantom. Comparing the data of clinical treatment, the differences were all <1 % among the prescription doses and the validation data collected from the self-design water phantom. However, the differences collected from the Plexiglas phantom were increasing gradually from +0.77 to +2.30 % along with increasing body width. Obviously, the difference had a positive correlation with the body width. The results proved that the new length-adjustable water phantom is more accurate for simulating human dimensions than Plexiglas phantom.
机译：开发了一种新型的水体模型，专门用于全身辐射（TBI）治疗中的吸收剂量测量。排列十毫米厚的有机玻璃板，以形成边长为300毫米的方形立方体。在侧壁上安装了合适的套筒式活塞，并在套筒内部放置了平板状的有机玻璃活塞。通过推拉活塞，可以改变自制水模的长度，以满足所需的患者身体尺寸。为了将国际标准水模与可调整长度的水模和有机玻璃体模进行比较，通过电离室在三种体模的不同深度测量了6-MV X射线的吸收剂量。在70例TBI患者中，使用可调节长度的Plexiglas幻影和人体模型对中平面剂量进行计量，以模拟人体尺寸，并同步进行剂量验证。通过对国际标准水体模型和自行设计的模型的数据进行统计处理，无统计学差异，p> 0.05。来自标准和有机玻璃的两组数据之间存在显着的统计学差异，p <0.05。此外，绝对差与有机玻璃体模中检测器的变化深度呈正相关。比较临床治疗数据，处方剂量和从自行设计的水模中收集的验证数据之间的差异均<1％。但是，从Plexiglas幻影收集的差异随着车身宽度的增加从+0.77逐渐增加到+ 2.30％。显然，差异与车身宽度呈正相关。结果证明，新的可调节长度的水体模比有机玻璃体模更精确地模拟人体尺寸。

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  • 来源
    《Radiation Protection Dosimetry》 |2012年第1期|p.89-94|共6页
  • 作者

    Zhi-Wei Chen; Sheng-Yu Yao; Tie-Ning Zhang; Zhen-Hua Zhu; Zhe-Kai Hu; Xun Lu;

  • 作者单位

    Department of Oncology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China;

    Department of Oncology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China;

    Department of Oncology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China;

    Department of Oncology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China;

    Department of Oncology, First People's Hospital, Shanghai Jiaotong University, Shanghai 200080, China;

    Shanghai Institute of Measurement and Testing Technology, Shanghai 201203, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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