首页> 外文期刊>Russian journal of marine biology >Evaluation of the Genotoxicity of Cadmium in Gill Cells of the Clam Corbiculajaponica Using the Comet Assay1
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Evaluation of the Genotoxicity of Cadmium in Gill Cells of the Clam Corbiculajaponica Using the Comet Assay1

机译:彗星试验评估镉对Cor蛤G细胞的遗传毒性

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摘要

Cadmium-induced DNA degradation in gill cells of the clam Corbicula japonica was assessed using the comet assay (single-cell gel electrophoresis). Accumulation of highly toxic cadmium in the gill cells of bivalve is accompanied by damage to the cell genome, which is revealed as DNA migration in the comet assay. The main mechanisms of Cd effects on the integrity of the DNA structure are discussed.
机译:使用彗星测定法(单细胞凝胶电泳)评估了日本蛤bic的g细胞中镉诱导的DNA降解。双壳val细胞中高毒性镉的积累伴随着细胞基因组的破坏,这在彗星试验中显示为DNA迁移。讨论了镉对DNA结构完整性的影响的主要机理。

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