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首页> 外文期刊>Science of advanced materials >Size- and Morphology-Dependent Antibacterial Properties of Cuprous Oxide Nanoparticle and Their Synergistic Antibacterial Effect
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Size- and Morphology-Dependent Antibacterial Properties of Cuprous Oxide Nanoparticle and Their Synergistic Antibacterial Effect

机译：氧化亚铜纳米颗粒的大小和形态相关的抗菌特性及其协同抗菌作用

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摘要

Cuprous oxide nanoparticles with diverse morphology and particle size were prepared through reductive solution chemistry routes under alkaline condition. The standard minimal inhibitory concentration (MIC) test against Escherichia coli indicated that both size and morphology of cuprous oxide nanoparticles played important role in their antibacterial performance. Cuprous oxide nanoparticles with smaller size (similar to 50 nm) exhibited better antibacterial activity than those with larger size (250 similar to 350 nm); spherical cuprous oxide nanoparticles were found to be superior to the cubic ones in the bacterial killing process. In addition, the synergistic antibacterial effect of cuprous oxide nanoparticles in the presence of another antibacterial agent, ascorbic acid (AA), was investigated. Experimental results showed that the antibacterial capacity of cuprous oxide nanoparticles was significantly improved in the presence of ascorbic acid (0.1 wt%). The probable mechanism underlying the synergistic antibacterial activity has been discussed in detail. All the experimental results indicated that the developed low-cost antimicrobial mixture holds promising application potential.
机译：通过在碱性条件下的还原溶液化学路线制备了具有不同形态和粒径的氧化亚铜纳米粒子。针对大肠杆菌的标准最小抑菌浓度（MIC）测试表明，氧化亚铜纳米颗粒的大小和形态在其抗菌性能中均起着重要作用。较小尺寸（约50 nm）的氧化亚铜纳米颗粒显示出比较大尺寸（约250 nm至350 nm）更好的抗菌活性。球形氧化亚铜纳米颗粒在细菌杀灭过程中优于立方颗粒。此外，研究了在另一种抗菌剂抗坏血酸（AA）的存在下，氧化亚铜纳米颗粒的协同抗菌作用。实验结果表明，在抗坏血酸（0.1 wt％）存在的情况下，氧化亚铜纳米颗粒的抗菌能力显着提高。已详细讨论了协同抗菌活性的潜在机制。所有的实验结果表明，所开发的低成本抗菌剂混合物具有广阔的应用前景。

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  • 来源
    《Science of advanced materials》 |2016年第5期|1074-1078|共5页
  • 作者

    She Boxi; Wan Xuejuan; Tang Jiaoning; Deng Yuanming; Zhou Xiaofeng; Xiao Caihua;

  • 作者单位

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China|Qiling Middle Sch, Nanshan Expt Educ Grp, Shenzhen 518052, Peoples R China;

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China;

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China;

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China;

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China;

    Shenzhen Univ, Shenzhen Key Lab Special Funct Mat, Coll Mat Sci & Engn, Shenzhen 518060, Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Morphology; Particle Sizes; Cuprous Oxide; Antibacterial Property; Synergistic Effect;

    机译：形态;颗粒大小;氧化亚铜;抗菌性能;协同效应;

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