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Mode of Action of Killing of Microorganisms with Vasaka Leaf Extract

机译:瓦萨卡叶提取物杀死微生物的作用方式

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In studying the antimicrobial activity of Vasaka, it has been found that Vasaka leaf extract is a broad spectrum antimicrobiai agent and microbiostatic. When plates inoculated with microorganisms were grown in presence of Vasaka, no zone of inhibition was obtained. The organisms have grown resistance against Vasaka. The ethanolic extract of Vasaka have no direct effect on microbes like 5. mutans, Pseudomonas sp., Candida albicans and Aspergillus sp., but should trigger a signal, which would induce some cellular responses. Lastly, performing activity gel of SOD from cell extracts of microorganisms grown in presence of Vasaka extract indicated increased SOD activity. This gave the idea of the mechanism of killing of microbes.
机译:在研究瓦萨卡(Vasaka)的抗菌活性时,已发现瓦萨卡叶提取物是一种广谱抗微生物剂,具有抑菌作用。当在Vasaka存在下培养接种了微生物的平板时,未获得抑制区。这些生物已经对瓦萨卡产生了抵抗力。瓦萨卡(Vasaka)的乙醇提取物对变形菌,假单胞菌(Pseudomonas sp。),白色念珠菌(Candida albicans)和曲霉(Aspergillus sp。)等微生物没有直接影响,但应触发信号,从而诱导某些细胞反应。最后,对在Vasaka提取物存在下生长的微生物的细胞提取物进行SOD活性凝胶分析表明,SOD活性增加。这给出了杀死微生物的机制的想法。

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