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ANTIBIOTIC ABUSE : A THREAT TO HUMAN HEALTH

机译:抗生素滥用:对人类健康的威胁

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摘要

Antibiotics drugs are chemical compounds which are used to control bacterial infections. They are classified in different forms according to their mode of action against pathogens. There are more than 40,000 brands of antibiotics available in market in different formulations for the treatment by humans and animals around the world e.g., quinolones, macrolides, cephalosporins, aminoglycosides etc. Excessive and uncontrolled use of these drugs has created resistant microbes which pose serious health hazards to humans. Plasmid, which is an extra-nucleur circular DNA (Deoxyribose Nucleic Acid) in microbes, causes resistance against the antibiotics. The main cause behind the rise of multi-resistant pathogens is abuse of antibiotics. International organizations like World Health Organization (WHO), Food and Drug administration (FDA) and United Nations (UN) have identified the 'antibiotic abuse' as international concern. In this review, an attempt has been made to study the various factors responsible for the abuse of antibiotics in prevalent Indian conditions. It includes ignorance of people, self medication, unhygienic conditions and sometimes wrong medical prescription.
机译:抗生素药物是用于控制细菌感染的化合物。根据它们对病原体的作用方式,将它们分为不同的形式。市场上有超过40,000个品牌的抗生素,它们以不同的配方供世界各地的人类和动物使用,例如喹诺酮类,大环内酯类,头孢菌素类,氨基糖苷类等。过度和无节制地使用这些药物已经产生了抗药性微生物,严重危害健康对人类的危害。质粒是微生物中的一种核外环状DNA(脱氧核糖核酸),对抗生素产生抗药性。多重耐药病原体兴起的主要原因是滥用抗生素。世界卫生组织(WHO),食品药品管理局(FDA)和联合国(UN)等国际组织已将“抗生素滥用”确定为国际关注的焦点。在这篇综述中,人们试图研究导致印度流行的抗生素滥用的各种因素。它包括人们的无知,自我用药,不卫生的状况以及有时错误的医疗处方。

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