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PARACRINE REGULATION OF THE ADRENAL GLAND

机译:肾上腺调节

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摘要

The traditional concept regarding the anatomical closeness between adrenal cortex and medulla bears no apparent functional significance. However, there is now sufficient evidence that the products of each of these tissues may influence the function of the other (Paracrine effect). It is well established that Glucocorticoids secreted by the cortex are drained through the blood vessels and regulates the conversion of Norepinephrine (NE) to Epinephrine (E). Indeed, more intriguing, is the question of how medullary products can reach the cortex and modulate the cortical function. The neural pathway connecting medulla to cortex is probably the most candid answer. In support of this several neuropeptides and biogenic amines are identified in the adrenal cortex and further the source of these neurotransmitters being the perikarya associated with medullary tissue. These neural products in turn may modulate glucocorticoid synthesis/ secretion through a paracrine mode of communication.
机译:关于肾上腺皮质和髓质之间的解剖学紧密性的传统概念没有明显的功能意义。但是,现在有足够的证据表明,这些组织中每种组织的产物都可能影响另一种组织的功能(Paracrine效应)。众所周知,皮层分泌的糖皮质激素通过血管排出,并调节去甲肾上腺素(NE)向肾上腺素(E)的转化。确实,更有趣的是髓质产物如何到达皮质并调节皮质功能的问题。连接髓质和皮层的神经途径可能是最坦率的答案。为了支持这一点,在肾上腺皮质中鉴定了几种神经肽和生物胺,并且进一步地,这些神经递质的来源是与髓样组织相关的核周膜。这些神经产物进而可以通过旁分泌的交流方式调节糖皮质激素的合成/分泌。

著录项

  • 来源
    《Science and Culture》 |2002年第8期|p.180-181|共2页
  • 作者

    ASOK GHOSH;

  • 作者单位

    Histophysiology Laboratory, Department of Zoology, University of Calcutta, 35 Ballygunge Circular Road, Kolkata-700 019, India;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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