...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Science and Technology of Advanced Materials >Hydrogels having tubular α-cyclodextrin structure: effect of nano-tube structure on long alkyl chain partitions
【24h】

Hydrogels having tubular α-cyclodextrin structure: effect of nano-tube structure on long alkyl chain partitions

机译：具有管状α-环糊精结构的水凝胶：纳米管结构对长烷基链间隔的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

New hydrogels having the tubular structure of α-cyclodextrins (α-CDs) crosslinked by poly(ethylene glycol) (PEG) (MT-PEG hydrogels) were prepared by using a hydrolyzable polyrotaxane. The hydrolyzable polyrotaxane, in which many α-CDs are threaded onto a PEG chain capped by a hydrolyzable ester moiety, was used to form a tubular structure in the hydrogel. After crosslinking with another PEG chain, the ester linkage in the polyrotaxane was hydrolyzed in 1N NaOH. This led to exposing hydrophobic cavity of α-CDs. The tubular-structured hydrogel incorporated sodium dodecyl sulfate (SDS) much faster than normally crosslinked α-CDs hydrogel (α-CD-PEG hydrogel). Furthermore, partition coefficient (K) of SDS to the MT-PEG hydrogel was two times larger than the α-CD-PEG hydrogel. These results suggest that the tubular structure of α-CDs, made from a template of the polyrotaxane, is much more attractive to include SDS in the α-CD cavities. Unsaturated fatty acids (palmitoleic acid (C16:l) and oleic acid (C18:l)) were also effectively incorporated into the tubular-structured hydrogel during 6 days. The K value of C16:1 was as the same order in magnitude as C 18:1. Thus, the tubular structure of α-CDs was advantageous to incorporate long alkyl chains into the hydrophobic cavity of α-CDs in aqueous conditions.
机译：通过使用可水解的聚轮烷制备具有通过聚（乙二醇）（PEG）交联的α-环糊精（α-CD）的管状结构的新型水凝胶（MT-PEG水凝胶）。使用可水解的聚轮烷，其中许多α-CD螺纹连接到由可水解的酯部分覆盖的PEG链上，用于在水凝胶中形成管状结构。与另一个PEG链交联后，聚轮烷中的酯键在1N NaOH中水解。这导致暴露出α-CD的疏水腔。管状结构的水凝胶掺入十二烷基硫酸钠（SDS）的速度比正常交联的α-CDs水凝胶（α-CD-PEG水凝胶）快得多。此外，SDS与MT-PEG水凝胶的分配系数（K）是α-CD-PEG水凝胶的两倍。这些结果表明，由聚轮烷的模板制成的α-CD的管状结构具有更大的吸引力，可以将SDS包含在α-CD腔中。不饱和脂肪酸（棕榈油酸（C16：l）和油酸（C18：l））在6天之内也有效地掺入了管状结构的水凝胶中。 C16：1的K值在数量级上与C 18：1相同。因此，α-CD的管状结构有利于在水性条件下将长烷基链掺入α-CD的疏水腔中。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号