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首页> 外文期刊>The Science of the Total Environment >Lipophilicity of PCBs and fatty acids determines their mobilisation from blubber of weaned northern elephant seal pups
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Lipophilicity of PCBs and fatty acids determines their mobilisation from blubber of weaned northern elephant seal pups

机译：多氯联苯和脂肪酸的亲脂性决定了它们从断奶的北象海豹幼崽的脂肪中迁移的能力

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摘要

Polychlorinated biphenyls (PCBs) exhibit lipophilic properties that lead to their bioaccumulation in adipose tissue. Following PCB exposition, northern elephant seals (Mirounga angustirostris) concentrate high amounts of these pollutants in their large adipose tissue stores. During lipolytic periods such as the post-weaning fast, fatty acids (FAs), which form triglycerides, and PCBs are both mobilised from adipose tissue. Our results showed that the degree of lipophilicity of FAs and PCBs impacted their release: the more lipophilic FAs and PCBs tended to be more conserved in blubber over the fast than the less lipophilic ones. This led to an enrichment of more lipophilic compounds within adipocytes with the progression of the fast Life history patterns that include fasting may thus influence the profile of blubber lipids and contaminants.
机译：多氯联苯（PCB）具有亲脂性，导致其在脂肪组织中的生物蓄积。在PCB暴露后，北部象海豹（Mirounga angustirostris）将大量的这些污染物集中在它们的大型脂肪组织存储中。在断奶后禁食等脂解期间，形成甘油三酸酯的脂肪酸（FAs）和PCBs均从脂肪组织中迁移出来。我们的结果表明，FA和PCB的亲脂性程度影响了它们的释放：与脂亲性较低的FA和PCB相比，脂族FA和PCB越快，其在脂液中的保存性越高。随着包括禁食在内的快速生活史模式的发展，这导致脂肪细胞中更多亲脂性化合物的富集可能因此影响了脂脂和污染物的分布。

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  • 来源
    《The Science of the Total Environment》 |2016年第15期|599-602|共4页
  • 作者

    Caroline Louis; Adrian Covaci; Daniel E. Crocker; Cathy Debier;

  • 作者单位

    Institut des Sciences de la Vie, UCLouvain, Croix du Sud 2/L7.05.08, 1348 Louvain-la-Neuve, Belgium;

    Department of Pharmaceutical Sciences, Taxicological Center, Campus Drie Eiken, Universiteit Antwerpen, Universiteitsplein 1, 2610 Wilrijk, Belgium;

    Department of Biology, Sonoma State University, 1801 East Cotati Ave, Rohnert Park, CA 94928, USA;

    Institut des Sciences de la Vie, UCLouvain, Croix du Sud 2/L7.05.08, 1348 Louvain-la-Neuve, Belgium;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Polychlorinated biphenyls; Fatty acids; Adipose tissue; Lipolysis;

    机译：多氯联苯;脂肪酸;脂肪组织;脂解;

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