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首页> 外文期刊>The Science of the Total Environment >Nitrogen dioxide and asthma emergency department visits in California, USA during cold season (November to February) of 2005 to 2015: A time-stratified case-crossover analysis
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Nitrogen dioxide and asthma emergency department visits in California, USA during cold season (November to February) of 2005 to 2015: A time-stratified case-crossover analysis

机译：2005年至2015年的寒冷季节（11月至2月）在美国加州加州的二氧化氮和哮喘急诊部门访问：时间分层案例交叉分析

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摘要

Nitrogen dioxide (NO_2) is responsible for aggravating respiratory diseases, particularly asthma. The aim of this study is to investigate the association between NO_2 exposure and asthma emergency department (ED) visits during the cold season (November-February) in five populated locations (Sacramento, San Francisco, Fresno, Los Angeles, and San Diego) of California from 2005 to 2015 (1320 Days). Conditional logistic regression models were used to obtain the odds ratio (OR) and 95% confidence interval (CI) associated with a 5 ppb increase in NO_2 concentration for the 19,735 ED visits identified. An increase in NO_2 exposure increased the odds of having asthma ED visits for the studied population. The potential effect modification by sex (female and male), race (White, Black, Hispanic, and Asian), and age (2-5,6-18,19-40.41 -64, and ≥65) was explored. A 5 ppb increase in the concentration of NO_2 during lag 0-30 was associated with a 56% increase in the odds of having an asthma ED visit (OR = 1.560, CI: 1.428-1.703). Sex was not found to be a modifier. Asthma ED visits among all the races/ethnicities (except Asians) were associated with NO_2 exposure. Whites had the highest OR 75% (OR = 1.750, CI: 1.417-2.160) at lag 0-30 in response to NO_2 exposure. The association between NO_2 exposure and asthma ED visits was positive among all age groups except for 19 to 40 years old; the OR was higher among 2 to 18 year old (at lag 0-30: age group 2-5 (OR = 1.699, CI: 1.399-2.062), and age group 6-18 (OR = 1.568, CI 1.348-1.825)). For stratification by location, San Diego and Fresno were found to have the highest OR, compared to the other studied locations.
机译：二氧化氮（NO_2）负责加重呼吸系统疾病，特别是哮喘。本研究的目的是调查NO_2暴露和哮喘急诊部（ED）在寒冷季节（11月至2月）之间的关联（萨克拉门托，旧金山，弗雷斯诺，洛杉矶和圣地亚哥）的访问加利福尼亚州从2005年到2015年（1320天）。有条件的逻辑回归模型用于获得与鉴定的19,735次申请的NO_2浓度的5ppb增加相关的差距（或）和95％置信区间（CI）。 NO_2曝光的增加增加了对研究人群的哮喘访问的几率。探讨了性别（女性和男性），种族（白色，黑色，西班牙裔和亚洲人）和年龄（2-5,6-18,19-40.41 -64和≥65）的潜在效果修改。在LAG 0-30期间NO_2浓度增加5ppb与哮喘eD访问的可能性增加56％（或= 1.560，CI：1.428-1.703）。没有发现性是一个修饰者。所有比赛/种族（亚洲人除外）之间的哮喘访问与NO_2曝光有关。 White响应于NO_2曝光，白人的滞后0-30具有最高或75％（或= 1.750，CI：1.417-2.160）。除了19至40岁以下的所有年龄组之间，NO_2曝光和哮喘eD访问之间的关联是阳性的; 2至18岁之间的或更高（滞后0-30：年龄组2-5（或= 1.699，CI：1.399-2.062），年龄组6-18（或= 1.568，CI 1.348-1.825） ）。对于位置的分层，发现圣地亚哥和弗雷斯诺与其他研究的位置相比，已经找到了最高的或。

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