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Design and Simulation of a High Sensitive Surface Plasmon Resonance Biosensor for Detection of Biomolecules

机译:高敏感表面等离子体共振生物传感器检测生物分子的设计与仿真

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摘要

In this paper, a surface plasmon resonance (SPR) biosensor based on black phosphorus (BP)–WSe_2 coated metal surface for the detection of biomolecules is designed and simulated. The reported sensor configuration consists of a prism (SF10 glass), ZnO (zinc oxide), gold (Au), WSe_2– BP, and sensing medium. The execution parameters including sensitivity, detection accuracy, and quality factor of the proposed sensor are explored at an operating wavelength of 633 nm. The angular interrogation method is used for the reflectance spectra analysis. The overall simulation is performed by COMSOL multiphysics (5.3a). Numerical outcomes demonstrate that the base ZnO layers which have an expansive genuine value of the dielectric constant in a mix with gold, WSe_2, and BP are in charge of upgrading the detecting execution of the proposed SPR based biosensor. The reported biosensor achieves maximum sensitivity of 101.5 deg/RIU, the detection accuracy of 1.57 and a quality parameter of 15.62 RIU−1 for a large dynamic range of refractive index differing from 1.33 to 1.43.
机译:在本文中,设计并模拟了基于黑磷(BP)-WSE_2涂覆金属表面的表面等离子体共振(SPR)生物传感器。报告的传感器配置包括棱镜(SF10玻璃),ZnO(氧化锌),金(Au),WSE_2-BP和传感介质。包括所提出的传感器的灵敏度,检测精度和质量因子的执行参数在633nm的工作波长下探索。角度询问方法用于反射谱分析。整体模拟由COMSOL Multiphysics(5.3a)执行。数值结果表明,具有金,WSE_2和BP的混合中具有介电常数的膨胀真正值的基础ZnO层负责升级所提出的基于SPR基生物传感器的检测执行。报告的生物传感器实现了101.5°/ RiU的最大灵敏度,检测精度为1.57,质量参数为15.62 riu-1,对于从1.33到1.43的折射率的大动态折射率范围。

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