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首页> 外文期刊>Sensing and imaging >A Method of Time–Intensity Curve Calculation for Vascular Perfusion of Uterine Fibroids Based on Subtraction Imaging with Motion Correction
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A Method of Time–Intensity Curve Calculation for Vascular Perfusion of Uterine Fibroids Based on Subtraction Imaging with Motion Correction

机译：基于运动校正相减成像的子宫肌瘤血管灌注时间-强度曲线计算方法

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摘要

The time–intensity curve (TIC) from contrast-enhanced ultrasoundrn(CEUS) image sequence of uterine fibroids provides important parameter informationrnfor qualitative and quantitative evaluation of efficacy of treatment such asrnhigh-intensity focused ultrasound surgery. However, respiration and other physiologicalrnmovements inevitably affect the process of CEUS imaging, and this reducesrnthe accuracy of TIC calculation. In this study, a method of TIC calculation forrnvascular perfusion of uterine fibroids based on subtraction imaging with motionrncorrection is proposed. First, the fibroid CEUS recording video was decoded intornframe images based on the record frame rate. Next, the Brox optical flow algorithmrnwas used to estimate the displacement field and correct the motion between twornframes based on warp technique. Then, subtraction imaging was performed tornextract the positional distribution of vascular perfusion (PDOVP). Finally, thernaverage gray of all pixels in the PDOVP from each image was determined, and thisrnwas considered the TIC of CEUS image sequence. Both the correlation coefficientrnand mutual information of the results with proposed method were larger than thoserndetermined using the original method. PDOVP extraction results have beenrnimproved significantly after motion correction. The variance reduction rates were allrnpositive, indicating that the fluctuations of TIC had become less pronounced, andrnthe calculation accuracy has been improved after motion correction. This proposed method can effectively overcome the influence of motion mainly caused by respirationrnand allows precise calculation of TIC.
机译：子宫肌瘤造影剂超声图像的时间强度曲线（TIC）为定性和定量评估诸如高强度聚焦超声手术的疗效提供了重要的参数信息。然而，呼吸和其他生理运动不可避免地影响CEUS成像过程，这降低了TIC计算的准确性。本文提出了一种基于运动校正的减影成像技术对子宫肌瘤血管灌注的TIC计算方法。首先，基于记录帧率将肌瘤CEUS记录视频解码为帧图像。接下来，使用了Brox光流算法来估计位移场并基于翘曲技术校正两个框架之间的运动。然后，进行减影成像以提取血管灌注（PDOVP）的位置分布。最终，确定每个图像的PDOVP中所有像素的平均灰度，并将其视为CEUS图像序列的TIC。所提方法的相关系数和互信息均大于用原方法确定的结果。运动校正后，PDOVP提取结果已得到显着改善。方差减小率是正的，表明TIC的波动变得不太明显，并且运动校正后的计算精度得到了提高。该方法可以有效克服呼吸运动引起的运动影响，并可以精确计算出TIC。

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  • 来源
    《Sensing and imaging》 |2016年第1期|19.1-19.14|共14页
  • 作者

    Xinjian Zhu; Ruoyu Wu; Tao Li; Dawei Zhao; Xin Shan; Puling Wang; Song Peng; Faqi Li; Baoming Wu;

  • 作者单位

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, ChinaState Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing andthe Ministry of Science and Technology, College of Biomedical Engineering, ChongqingMedical University, Chongqing 400042, China;

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, China;

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, China;

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, China;

    State Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing andthe Ministry of Science and Technology, College of Biomedical Engineering, ChongqingMedical University, Chongqing 400042, China;

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, China;

    State Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing andthe Ministry of Science and Technology, College of Biomedical Engineering, ChongqingMedical University, Chongqing 400042, China;

    State Key Laboratory of Ultrasound Engineering in Medicine Co-Founded by Chongqing andthe Ministry of Science and Technology, College of Biomedical Engineering, ChongqingMedical University, Chongqing 400042, China;

    State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, SurgeryInstitute of the Third Military Medical University, Chongqing 400042, China;

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  • 正文语种 eng
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  • 关键词

    Time–intensity curve; Motion correction; Subtraction imaging; Positional distribution of vascular perfusion;

    机译：时间-强度曲线;运动校正;减影成像;血管灌注的位置分布;

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