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Modular micropumps fabricated by 3D printed technologies for polymeric microfluidic device applications

机译：用于聚合物微流体装置应用的3D印刷技术制造的模块化微型泵

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摘要

In order to facilitate the implementation of microfluidic technology for rapid point-of-care analysis, there is a demand for self-powered microfluidics. The modular architecture of degas driven plug-and-play polymeric micropumps and microfluidic cartridges arose during last decade as a powerful strategy for autonomous flow control. So far, reported polymeric micropumps were made of poly-dimethyl siloxane and were fabricated by casting. In this work, we showed that the advantages of three-dimensional printing can greatly benefit the development of modular micropumps. In addition, micropumps were created with a geometry that cannot be manufactured with conventional techniques, making it easily assemblable to microfluidic devices. Four types of polymeric resins and three printing methods were used to create a set of functional micropumps. It was shown that the material and the design of the printed micropumps were related to their power, making them tuneable and programmable. Finally, as proof of concept, a self-powered colorimetric test for the detection of starch was demonstrated. Three-dimensional printed micropumps emerge as an innovative element in the field of self-powered microfluidics, which may be the key to develop integrated microsystems for several applications such as in rapid point-of-care analysis.
机译：为了促进微流体技术的实施，以便快速护理点分析，需要对自我供电的微流体进行需求。 Degas驱动的即插即用聚合物微泵和微流体墨盒的模块化建筑在去年是一个强大的自主流量控制的强大战略。到目前为止，所报道的聚合物微泵由聚 - 二甲基硅氧烷制成，并通过铸造制造。在这项工作中，我们认为三维印刷的优点可以极大地利用模块化微泵的发展。此外，使用几何形状产生微泵，该几何形状不能用常规技术制造，使其容易地组装到微流体装置。使用四种类型的聚合物树脂和三种印刷方法来产生一组功能微泵。结果表明，印刷微泵的材料和设计与其动力有关，使它们可调和可编程。最后，作为概念证明，证明了对淀粉检测的自我功率比色试验。三维印刷微泵作为自动微流体领域的创新元素出现，这可能是为诸如在快速护理分析中开发若干应用的集成微系统的关键。

著录项

  • 来源
    《Sensors and Actuators》 |2021年第9期|129991.1-129991.8|共8页
  • 作者

    Y. Alvarez-Brana; J. Etxebarria-Elezgarai; L. Ruiz de Larrinaga-Vicente; F. Benito-Lopez; L. Basabe-Desmonts;

  • 作者单位

    Microfluidics Cluster UPV/EHU BIOMICs microfluidics Group Lascaray Research Center University of the Basque Country UPV/EHU Vitoria-Gasteiz Spain Microfluidics Cluster UPV/EHU Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group Analytical Chemistry Department University of the Basque Country UPV/EHU Spain;

    Microfluidics Cluster UPV/EHU BIOMICs microfluidics Group Lascaray Research Center University of the Basque Country UPV/EHU Vitoria-Gasteiz Spain;

    Microfluidics Cluster UPV/EHU BIOMICs microfluidics Group Lascaray Research Center University of the Basque Country UPV/EHU Vitoria-Gasteiz Spain Microfluidics Cluster UPV/EHU Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group Analytical Chemistry Department University of the Basque Country UPV/EHU Spain;

    Microfluidics Cluster UPV/EHU Analytical Microsystems & Materials for Lab-on-a-Chip (AMMa-LOAC) Group Analytical Chemistry Department University of the Basque Country UPV/EHU Spain Bioaraba Health Research Institute Microfluidics Cluster UPV/EHU Vitoria-Gasteiz Spain BCMaterials Basque Center for Materials Applications and Nanostructures UPV/EHU Science Park Leioa Spain;

    Microfluidics Cluster UPV/EHU BIOMICs microfluidics Group Lascaray Research Center University of the Basque Country UPV/EHU Vitoria-Gasteiz Spain Bioaraba Health Research Institute Microfluidics Cluster UPV/EHU Vitoria-Gasteiz Spain BCMaterials Basque Center for Materials Applications and Nanostructures UPV/EHU Science Park Leioa Spain Basque Foundation of Science IKERBASQUE Maria Diaz Haroko Kalea 3 Bilbao 48013 Spain;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Self-powered microfluidics; Micropumps; Degas driven flow; 3D printing; Stereolithography; Starch-lugol reaction;

    机译：自动微流体;微泵;Degas驱动流动;3D打印;立体刻录;淀粉 - 卢瓦尔反应;

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