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Ion Sensor for the Quantification of Sodium in Sweat Samples

机译:离子传感器,用于定量检测汗液中的钠

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摘要

We present the conception of an electrochemical sodium ion sensor for point-of-care sweat analysis. This flexible amperometric sensor was developed to quantify the amount of sodium ions in sweat (in real-time), alleviating the wait time, large sample size, possible contamination, and expensive analytical equipment associated with current diagnostic procedures requiring sweat analysis. This sensor is composed of a multiwall carbon nanotube (MWNT) functionalized nylon-6 mat, for a flexible yet conductive sensor. The MWNTs are then functionalized with a cyclo-oligomeric calixarene, which is shown to selectively form a supramolecular complex with sodium ions. Upon complex formation, the charge carriers are drawn away from the carbon layer, hence the current is impeded, and the sodium ion detection is prevalent at appropriate physiological ranges for healthy and ailing humans. In this paper, the optimization of MWNT and calixarene functionalization, as well as the selectivity and sensitivity of the sensor will be discussed.
机译:我们提出了一种用于护理现场汗液分析的电化学钠离子传感器的概念。这款灵活的安培传感器旨在实时定量分析汗液中钠离子的量,从而减少了等待时间,大样本量,可能的污染以及与当前需要汗液分析的诊断程序相关的昂贵分析设备。该传感器由多壁碳纳米管(MWNT)功能化的尼龙6垫组成,用于柔性但导电的传感器。然后用环-低聚杯芳烃官能化MWNT,后者显示出与钠离子选择性形成超分子络合物。在形成复合物时,电荷载流子从碳层中抽出,因此电流受到阻碍,钠离子检测在健康和患病人类的适当生理范围内普遍存在。在本文中,将讨论MWNT和杯芳烃功能化的优化,以及传感器的选择性和灵敏度。

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