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An Integrated Biological Analysis and Flow Rate Sensing for the Real-Time Detection of Carcinogen in Water Based on Co2+-Doped Optical Fibers

机译:基于CO2 +掺杂光纤的水中致癌物实时检测的综合生物学分析及流速感测

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摘要

The multi-parameter measurement has significant meaning for biosensor to enhance their practical sensing performance. For the biological detection, simultaneous measurement of biological molecule and flow rate could improve the accuracy and sensitivity of sensors significantly. In this paper, an integrated biological analysis and flow rate sensing based on Co2+ doped tilted fiber Bragg gratings has been proposed and experimentally demonstrated for real-time the detection of the Benzo[a]pyrene molecules. A tilted fiber Bragg grating with a tilted angle of 8 degrees; was inscribed into a Co2+ doped fiber. The flow rate and Benzo[a]pyrene molecules can be measured simultaneously by interrogating the resonance wavelength of core mode and wavelength interval between the core mode and cladding mode according to the heat exchange and evanescent field of the cladding mode, respectively. Experimental results show that the real-time measurement sensitivities of 12 pm/pM and -0.13 nm/(mu L/s) for the Benzo[a]pyrene detection and flow rate were achieved, respectively. Thus the technique appears to have potential applications in chemistry, medicine, and biology.
机译:多参数测量对生物传感器具有重要意义,以提高其实际感测性能。对于生物检测,同时测量生物分子和流速可以显着提高传感器的精度和敏感性。本文已经提出了基于CO2 +掺杂倾斜光纤布拉格光栅的集成生物分析和流量检测,并实验证明了苯并[a]芘分子的检测。倾斜光纤布拉格光栅,倾斜角度为8度;被铭刻成CO2 +掺杂纤维。通过根据包层和覆盖模式的热交换和浮雕场之间询问芯模式和覆盖模式之间的核心模式和波长间隔的共振波长,可以同时测量流速和苯并[a]芘分子。实验结果表明,苯并[a]芘检测和流速的实时测量敏感性分别为苯并[a]芘检测和流速。因此,该技术似乎具有化学,医学和生物学中的潜在应用。

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