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Microfluidic flow rate detection based on integrated optical fiber cantilever

机译:基于集成光纤悬臂的微流率检测

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摘要

We demonstrate an integrated microfluidic flow sensor with ultra-wide dynamic range, suitable for high throughput applications such as flow cytometry and particle sorting/counting. A fiber-tip cantilever transduces flow rates to optical signal readout, and we demonstrate a dynamic range from 0 to 1500 mu L min(-1) for operation in water. Fiber-optic sensor alignment is guided by preformed microfluidic channels, and the dynamic range can be adjusted in a one-step chemical etch. An overall non-linear response is attributed to the far-field angular distribution of single-mode fiber output.
机译:我们展示了具有超宽动态范围的集成微流传感器,适用于高通量应用,例如流式细胞仪和颗粒分选/计数。光纤尖端的悬臂将流量转换为光信号读数,并且我们证明了在水中运行的动态范围是0至1500μL min(-1)。光纤传感器的对准是通过预先形成的微流体通道进行的,动态范围可以一步化学蚀刻来调节。整体非线性响应归因于单模光纤输出的远场角度分布。

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