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Separation of static and dynamic sources in absence epileptic seizures using depth cortical measurements

机译:使用深度皮层测量分离没有癫痫发作的静态和动态源

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摘要

In this study, we analyze the absence epileptic seizures using the data recorded from different layers of somatosensory cortex of absence epileptic rats. We aim to (1) extract the epileptic activities or sources generating the seizures, and (2) investigate the temporal changes of seizures. To achieve our goals, we describe the recorded seizures by a linear superposition of static and dynamic sources. The static sources are stable and have a fixed structure, while the dynamic sources can be intermittent, and may be with different locations. Retrieving the sources and their structures from the recorded seizures helps us to achieve the desired analysis. Experimental results show the existence of a static source and three specific dynamic sources during the recorded seizures. The dynamic sources randomly activate with the static source and one of them disappears towards the end of the seizures. Moreover, it is shown that the spatial locations of the sources are similar in different absence epileptic rats. (C) 2019 Elsevier B.V. All rights reserved.
机译:在这项研究中,我们使用从失神癫痫大鼠的体感皮层的不同层记录的数据来分析失神癫痫发作。我们的目的是(1)提取癫痫活动或癫痫发作的来源,以及(2)研究癫痫发作的时间变化。为了实现我们的目标,我们通过静态和动态来源的线性叠加来描述记录的癫痫发作。静态源是稳定的并具有固定的结构,而动态源可以是间歇性的,并且可能位于不同的位置。从记录的癫痫发作中检索来源及其结构有助于我们进行所需的分析。实验结果表明,在记录的癫痫发作中存在一个静态来源和三个特定的动态来源。动态源与静态源随机激活,其中之一在癫痫发作结束时消失。而且,显示出在不同的缺席癫痫大鼠中源的空间位置是相似的。 (C)2019 Elsevier B.V.保留所有权利。

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