A randomized two stage allocation for continuous response clinical trials

Bhattacharya Rahul; Shome Madhumita

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A randomized two stage allocation for continuous response clinical trials

机译：连续两阶段临床试验的随机两阶段分配

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摘要

A randomized two treatment allocation design, conducted in two stages, is proposed for a class of continuous response trials. Patients are assigned to each treatment in equal numbers in the first stage and p value of a test of equality of treatment effects based on these data is used to determine the assignment probability of second stage patients. Relevant properties of the proposed allocation design are investigated and compared with suitable competitors.

机译：对于一类连续反应试验，提出了分两个阶段进行的随机两种治疗分配设计。在第一阶段将患者分配给相等数量的每种疗法，并根据这些数据使用治疗效果相等性测试的p值来确定第二阶段患者的分配概率。拟议的分配设计的相关属性进行了调查，并与合适的竞争对手进行了比较。

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来源
《Statistical Methods and Applications》 |2015年第3期|373-386|共14页
作者
Bhattacharya Rahul; Shome Madhumita;
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作者单位

Univ Calcutta, Dept Stat, Kolkata 700019, India;

Krishna Kumar Hindu Acad, Kolkata 700074, India;

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原文格式 PDF
正文语种 eng
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关键词
Two stage allocation; Clinical trials; p value;

机译：两阶段分配;临床试验;p值;

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A randomized two stage allocation for continuous response clinical trials

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