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Anticipating governance challenges in synthetic biology: Insights from biosynthetic menthol

机译:预测合成生物学中的治理挑战:生物合成薄荷醇的见解

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摘要

This paper advances an anticipatory governance framework to investigate and prepare for the potential implications of an emerging technology. Within the growing domain of synthetic biology, we draw on an end-to-end assessment of biosynthetic menthol that incorporates consideration of multiple dimensions of production and use. Based on documentary analysis, available data, and interviews, our approach unfolds in three steps. First, we map the sociotechnical transition in menthol production, comparing existing agricultural and chemical production methods with new biosynthetic processes - or what we call the biological (bio) turn. Second, we explore the rationales, promises and expectations of menthol's bio-turn and explore the drivers of transition so as to clarify which goals and values innovation is addressing. Third, we reflect on the opportunities and challenges of such a transition to put forward an agenda for responsible innovation and anticipatory governance. The bio-turn in menthol is analysed through five responsible innovation dimensions: the potential distribution of benefits and burdens; social resilience; environmental sustainability; infrastructure and business models; and public perception and public interest. We consider the implications of our analysis both for the responsible development and application of synthetic biology for menthol and for the broader assessment and sociotechnical construction of emerging technologies.
机译:本文提出了一种预期的治理框架,以研究和准备新兴技术的潜在影响。在合成生物学不断发展的领域内,我们对生物合成薄荷醇进行了端到端评估,其中纳入了生产和使用的多个方面的考虑。基于文献分析,可用数据和访谈,我们的方法分为三个步骤。首先,我们绘制薄荷醇生产的社会技术转型图,将现有的农业和化学生产方法与新的生物合成过程(或我们称之为生物(生物)转向)进行比较。其次,我们探索薄荷醇生物转折的理由,希望和期望,并探索转型的驱动力,以明确创新所解决的目标和价值观。第三,我们反思这种过渡的机遇和挑战,以提出负责任的创新和预期治理的议程。通过五个负责任的创新维度来分析薄荷醇的生物转化:收益和负担的潜在分布;社会适应力;环境的可持续性;基础设施和商业模式;以及公众的看法和公共利益。我们考虑到分析对于薄荷醇合成生物学的负责任开发和应用以及对新兴技术的更广泛评估和社会技术构建的意义。

著录项

  • 来源
    《Technological forecasting and social change》 |2019年第2期|311-320|共10页
  • 作者单位

    Univ Manchester, Manchester Inst Innovat Res, Alliance Manchester Business Sch, Manchester M13 9PL, Lancs, England|Univ Manchester, Manchester Synthet Biol Res Ctr Fine & Special Ch, Manchester Inst Biotechnol, Manchester M1 7DN, Lancs, England;

    Univ Manchester, Manchester Inst Innovat Res, Alliance Manchester Business Sch, Manchester M13 9PL, Lancs, England|Univ Manchester, Manchester Synthet Biol Res Ctr Fine & Special Ch, Manchester Inst Biotechnol, Manchester M1 7DN, Lancs, England|Georgia Inst Technol, Sch Publ Policy, Atlanta, GA 30332 USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Sociotechnical transition; Anticipatory governance; Emerging technologies; Responsible research and innovation; Synthetic biology; Menthol;

    机译:社会技术转型;预期治理;新兴技术;负责任的研究与创新;合成生物学;薄荷醇;

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