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Metabolomics

机译：代谢组学

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In their quest to develop more-accurate medical diagnostic tests, researchers are turning to a new field called metabolomics—the analysis of the thousands of small molecules such as sugars and fats that are the products of metabolism. If metabolomic information can be translated into diagnostic tests, it could provide earlier, faster, and more accurate diagnoses for many diseases. Doctors have been measuring a few metabolites for decades to tell what's wrong with patients; glucose for diabetes is a familiar example. Metabolomics researchers, however, sort through hundreds of molecules to tease out a dozen or so that can serve as the signature of a particular disease. "We're hoping that many diseases will have metabolic fingerprints that we can measure," says Maren Laughlin, codirector of a new National Institutes of Health (NIH) metabolomics initiative. Initially, metabolic researchers are hunting for the signatures of conditions such as autism and Huntington's disease.
机译：为了寻求开发更精确的医学诊断测试，研究人员正在转向代谢组学这一新领域，即对代谢产物糖和脂肪等数千种小分子的分析。如果代谢组学信息可以转化为诊断测试，则可以为许多疾病提供更早，更快，更准确的诊断。数十年来，医生一直在测量几种代谢物，以告诉患者出了什么问题。葡萄糖是糖尿病的一个常见例子。然而，代谢组学研究人员对数百种分子进行分类，以筛选出十几种分子，这些分子可以作为特定疾病的标志。美国国立卫生研究院（NIH）新的代谢组学计划的联合主任马伦·劳克林（Maren Laughlin）说：“我们希望许多疾病都具有可以测量的代谢指纹。”最初，代谢研究人员正在寻找自闭症和亨廷顿氏病等疾病的特征。

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