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Präkanzerosen und Carcinomata in situ der Haut

机译:皮肤癌前和癌

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摘要

Precancerous skin lesions and carcinomas in situ of the skin represent the early stages of epithelial skin tumors. There is no invasive tumor growth, so the basement membrane is completely intact. These lesions show a wide variation of clinical and histological appearances on the skin or mucosa. The precancerous and carcinoma in situ lesions that are described in this text are actinic keratosis, actinic cheilitis, cutaneous horns, arsenical keratosis, tar-induced dermatosis, X-ray irradiation-related keratosis, Bowen’s disease, erythroplasia of Queyrat, bowenoid papulosis, intraepithelial neoplasia (vulvar, penile and anal). Because they all can progress into invasive carcinoma, therapy is mandatory. Many noninvasive therapeutic approaches exist nowadays in the form of gels, creams, photodynamic therapy and invasive techniques such as laser therapy and cryotherapy, curettage and excision of lesional skin. Depending on the treatment process, different rates of general clearance and recurrence of the lesions are discussed in this article.
机译:癌前皮肤病变和皮肤原位癌代表上皮性皮肤肿瘤的早期阶段。没有侵袭性肿瘤生长,因此基膜是完整的。这些病变在皮肤或粘膜上显示出广泛的临床和组织学外观变化。本文中描述的癌前和癌前病变是光化性角化病,光化性唇炎,皮肤角,砷性角化病,焦油引起的皮肤病,X射线辐射相关性角化病,鲍恩氏病,奎伊拉氏红斑,弓形丘疹,上皮内瘤形成(外阴,阴茎和肛门)。由于它们都可以发展为浸润性癌,因此必须进行治疗。如今,以凝胶,乳膏,光动力疗法和侵入性技术(例如激光疗法和冷冻疗法,刮除术和病变皮肤切除术)的形式存在许多非侵入性治疗方法。根据治疗过程的不同,本文讨论了不同的一般清除率和病变复发率。

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