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首页> 外文期刊>Thin Solid Films >Characterization and antibacterial performance of ZrCN/amorphous carbon coatings deposited on titanium implants
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Characterization and antibacterial performance of ZrCN/amorphous carbon coatings deposited on titanium implants

机译：钛植入物上沉积的ZrCN /非晶碳涂层的表征和抗菌性能

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摘要

Titanium (Ti)-based materials have been used for dental/orthopedic implants due to their excellent biological compatibility, superior mechanical strength and high corrosion resistance. The osseointegration of Ti implants is related to their composition and surface treatment. Better biocompatibility and anti-bacterial performances of Ti implant are beneficial for the osseointegration and for avoiding the infection after implantation surgery. In this study, nanocomposite ZrCN/amorphous carbon (a-C) coatings with different carbon contents were deposited on a bio-grade pure Ti implant material. A cathodic-arc evaporation system with plasma enhanced duct equipment was used for the deposition of ZrCN/a-C coatings. Reactive gas (N_2) and C_2H_2 activated by the zirconium plasma in the evaporation process were used to deposit the ZrCN/a-C coatings. To verify the susceptibility of implant surface to bacterial adhesion, Actinobacillus actinomycetemcomitans (A actinomy-cetemcomitans), one of the major pathogen frequently found in the dental implant-associated infections, was chosen for in vitro anti-bacterial analyses. In addition, the biocompatibility of human gingival fibroblast (HGF) cells on coatings was also evaluated by a cell proliferation assay. The results suggested that the ZrCN/a-C coatings with carbon content higher than 12.7 at.% can improve antibacterial performance with excellent HGF cell compatibility as well.
机译：钛（Ti）基材料由于其出色的生物相容性，卓越的机械强度和高耐腐蚀性而被用于牙科/整形外科植入物。 Ti植入物的骨整合与其组成和表面处理有关。 Ti植入物具有更好的生物相容性和抗菌性能，有利于骨整合和避免植入手术后的感染。在这项研究中，将具有不同碳含量的纳米复合ZrCN /非晶碳（a-C）涂层沉积在生物级纯Ti植入材料上。带有等离子增强风道设备的阴极电弧蒸发系统用于ZrCN / a-C涂层的沉积。锆等离子体在蒸发过程中活化的反应气体（N_2）和C_2H_2被用于沉积ZrCN / a-C涂层。为了验证植入物表面对细菌粘附的敏感性，选择了放线杆菌（Actinomycetemcomitans）（放线菌-cetemcomitans），这是在种植牙相关感染中经常发现的主要病原体之一，用于体外抗菌分析。另外，还通过细胞增殖测定法评价了人牙龈成纤维细胞（HGF）在涂层上的生物相容性。结果表明，碳含量高于12.7 at。％的ZrCN / a-C涂层也可以改善抗菌性能，同时具有出色的HGF细胞相容性。

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  • 来源
    《Thin Solid Films》 |2011年第5期|p.1525-1531|共7页
  • 作者

    Chih-Ho Lai; Yin-Yu Chang; Heng-Li Huang; Ho-Yi Kao;

  • 作者单位

    School of Medicine, China Medical University, Taichung, 404 Taiwan;

    Department of Mechanical and Computer-Aided Engineering, National Formosa University, Yunlin, Taiwan;

    School of Dentistry, China Medical University, Taichung, Taiwan;

    Department of Materials Science and Engineering, Mingdao University, Changhua, Taiwan;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    nanocomposite; antibacterial; biocompatibility; ZrCN; coating;

    机译：纳米复合材料抗菌;生物相容性ZrCN;涂层;

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