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首页> 外文期刊>Translational Stroke Research >The ABCD2 Score is Highly Predictive of Stroke in Minor Ischemic Stroke Patients
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The ABCD2 Score is Highly Predictive of Stroke in Minor Ischemic Stroke Patients

机译：ABCD2 评分可高度预测缺血性中风患者的中风

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Stroke risk prediction scores have been designed to stratify risk of recurrent cerebrovascular events in transient ischemic attack (TIA) and minor ischemic stroke (MIS) patients. Consecutive TIA or MIS patients referred to Ghaem Hospital, Mashhad were enrolled in a prospective cohort study during 2010–2011. Only TIA or MIS patients presenting within 24 h from the onset of symptoms were recruited. MIS was considered as ischemic stroke with NIHSS <4. The end point of the study was a new ischemic cerebrovascular event or vascular death at 90 days and additionally at 3 days. The decision to admit and treatment in each case was left to the discretion of the stroke neurologist. The predictive accuracy of the ABCD2 scoring system for recurrent stroke or TIA was quantified by the area under the cure (AUC) using the c statistics. Three hundred ninety-three TIA patients (238 males, 155 females) and 118 MIS patients (77 males, 41 females) were enrolled in the study. One hundred seventeen strokes (23.2%), 99 TIA (19.6%), and 11 vascular death (2.2%) occurred within 3 months postevent in the whole of our 511 patients with minor ischemic events. The ABCD2 score had a weak predictive value for 3 months and 3 days recurrent stroke in our TIA patients (AUC = 0.599, AUC = 0.591), but a high predictive value for 3 months and 3 days recurrent stroke in our MIS patients (AUC = 0.727, AUC = 0.728), respectively. The ABCD2 score is highly predictive of short-term recurrent stroke in MIS patients but not TIA cases, despite its creation for TIA cohorts.
机译：中风风险预测评分已被设计用于对短暂性脑缺血发作（TIA）和轻度缺血性中风（MIS）患者中复发性脑血管事件的风险进行分层。连续的TIA或MIS患者转诊至Mashhad的Ghaem医院，于2010-2011年进行了一项前瞻性队列研究。仅招募自症状发作后24小时内出现的TIA或MIS患者。 MIS被认为是NIHSS <4的缺血性中风。研究的终点是在90天和3天时发生了新的缺血性脑血管事件或血管死亡。在每种情况下，中风神经科医师有权决定是否接受和治疗。使用c统计量，通过治愈下面积（AUC）量化ABCD2 评分系统对复发性卒中或TIA的预测准确性。这项研究纳入了393名TIA患者（男238例，女155例）和118例MIS患者（77例男，41例女）。在我们的511例有轻微缺血事件的患者中，事件发生后3个月内发生了一百一十七次中风（23.2％），99例TIA（19.6％）和11例血管性死亡（2.2％）。在我们的TIA患者中，对于3个月和3天复发性卒中，ABCD2 评分的预测价值较弱（AUC = 0.599，AUC = 0.591），而对于MIS的患者，ABCD2 评分对3个月和3天复发性卒中的预测价值较高患者（AUC = 0.727，AUC = 0.728）。尽管ABCD2 评分是针对TIA队列创建的，但它可高度预测MIS患者而非TIA患者的短期复发性中风。

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