• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Tropical Animal Health and Production >Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health
【24h】

Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health

机译：患有特定乳腺炎的母牛在乳房内给药后消除牛奶中的红霉素：与剂量，挤奶频率和乳房健康的关系

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Elimination of erythromycin in milk following intramammary therapy of specific mastitis in cows was studied. Five cows received therapy in one quarter (G1), and eight in two quarters with five milked twice (G2) and three thrice a day (G3). Dose infused was 300 mg/quarter 12 h × 5 times. The drug concentrations in milk were determined using microbial assay technique with Micrococcus luteus as the test organism. Considerable variations occurred in the excretion of drug; levels for treated quarters being 8.25 to 37.61 μg/ml at first milking that declined rapidly at 24 h and no drug activity was observed beyond 36 h post treatment. In total, about 6–25% of the last infused dose appeared in the milk. Drug crossed to 1/15 quarter (G1), 6/10 quarters (G2) and all the six untreated quarters (G3). Crossover levels were significantly higher in mastitic quarters and for G3 cows, but duration of excretion remained same in all cases. It seems that crossover of erythromycin to untreated quarters is related to the udder health and dose infused.
机译：研究了在奶牛特定乳腺炎的乳房内治疗后消除牛奶中的红霉素。五分之一的母牛接受了四分之一的治疗（G1），四分之八接受了五次挤奶两次（G2），一天三三次的喂养（G3）。每季度注入300 mg的剂量12小时×5次。牛奶中的药物浓度是使用微生物测定技术确定的，以黄曲霉为测试生物。药物排泄发生了很大变化；刚开始挤奶时，处理季度的水平均水平为8.25至37.61μg/ ml，在24 h时迅速下降，并且在处理后36 h没有观察到药物活性。总的来说，最后注入剂量的6–25％出现在牛奶中。药物越过1/15季度（G1），6/10季度（G2）和所有六个未处理季度（G3）。乳腺和G3奶牛的交叉水平显着更高，但在所有情况下排泄的持续时间均相同。似乎红霉素与未治疗的四分之一的交叉与乳房健康和注入的剂量有关。

著录项

相似文献

  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号