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首页> 外文期刊>Tropical Animal Health and Production >Microsatellite-based genetic monitoring to detect cryptic demographic bottleneck in Indian riverine buffaloes (Bubalus bubalis)
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Microsatellite-based genetic monitoring to detect cryptic demographic bottleneck in Indian riverine buffaloes (Bubalus bubalis)

机译：基于微卫星的遗传监测可检测印度河水牛（Bubalus bubalis）的人口统计学瓶颈

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摘要

The present study was undertaken to evaluate different Indian riverine buffalo breeds (Bubalus bubalis) for mutation drift equilibrium and occurrence of any recent genetic bottleneck. A total of 330 animals from seven different breeds were analyzed with a set of 24 heterologous microsatellite markers. Three different tests revealed significant heterozygosity excess in all the seven buffalo breeds studied when assumed under infinite alleles model of microsatellite evolution, while it was the reverse with no significant heterozygosity excess when assumed under conservative stepwise mutation model. Under the two-phase model, all the buffalo breeds except Mehsana were found to be in mutation drift equilibrium when evaluated by all the three statistical methods. Standardized differences test and Wilcoxon signed-rank test revealed significant heterozygosity excess suggesting possible cryptic demographic bottleneck in Mehsana buffaloes of Western India.
机译：本研究旨在评估不同的印度河水牛品种（Bubalus bubalis）的突变漂移平衡和任何近期的遗传瓶颈的发生。用一组24种异源微卫星标记对来自七个不同品种的330只动物进行了分析。在微卫星进化的无限等位基因模型下进行假设时，三种不同的测试揭示了所研究的所有七个水牛品种中均存在显着的杂合度过剩，而在保守的逐步突变模型中进行假设时，则没有明显的杂合度过高。在两阶段模型下，当通过三种统计方法进行评估时，发现除Mehsana之外的所有水牛都处于突变漂移平衡。标准化差异检验和Wilcoxon秩和检验表明显着的杂合度过剩，这表明印度西部Mehsana水牛可能存在人口统计学的瓶颈。

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