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Prevalence and mortality rate of peste des petitis ruminant (ppr): possible association with abortion in goat

机译:瘟疫反刍动物(ppr)的患病率和死亡率:可能与山羊流产有关

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摘要

Present study was designed to investigate the prevalence and mortality (%) caused by Peste des Petitis Ruminant (PPR) and its possible association with abortion in goat flocks at different areas of Pakistan. A total of 140 animals were samples in the population of 650 which was having 185 deaths (Mortality rate = 28 %) from three different regions of the country. There were 58 abortions in the 140 pregnant goats of above said population One hundred & ten (110) serum samples from diseased, recovered and apparently healthy animals were tested for the presence of PPR antibodies by competitive ELISA (c ELISA). Eighty-four (84) animals were positive for PPR antibodies whereas in apparently healthy adult goats in the same flock, no PPR antibodies were detected. Twenty-four (24) tissue samples collected from the dead animals and six samples from aborted fetus were tested for the presence of PPR antigen by Immuno-capture ELISA (Ic ELISA). Nineteen (19) out of thirty (30) organ samples mainly from lung, spleen, lymph node were found positive for PPR antigen but negative from lungs of aborted fetus. There was a high rate of abortions (28–45 %) in each of the outbreak and it was highest in the outbreak of Golra Sharif, Islamabad (No. = 21 in total population of 100). As the serum samples from the aborted dams were found positive for PPR antibodies so the study provides the possible association of mortality and prevalence of PPR disease with high rate of abortions in goat.
机译:本研究旨在调查由小反刍兽疫(PPR)引起的患病率和死亡率(%),以及其与巴基斯坦不同地区山羊群中流产的可能关系。在该国650个人口中,共有140只动物为样本,在该国三个不同地区有185例死亡(死亡率)(28%)。在上述种群的140只怀孕的山羊中,有58次流产。通过竞争ELISA(c ELISA)测试了一百十(110)名患病,康复和显然健康的动物的血清样品中PPR抗体的存在。八十四(84)只动物的PPR抗体呈阳性,而在同一群羊中显然健康的成年山羊中,未检测到PPR抗体。通过免疫捕获ELISA(Ic ELISA)测试了从死动物中收集的二十四(24)个组织样品和流产胎儿的六个样品中PPR抗原的存在。在三十(30)个主要来自肺,脾,淋巴结的器官样本中,有十九(19)个对PPR抗原呈阳性,但在流产胎儿的肺中呈阴性。每次爆发的流产率都很高(28–45%),在伊斯兰堡的古拉·谢里夫(Golra Sharif)的爆发中流产率最高(在100个总人口中为21)。由于发现来自流产大坝的血清样本中的PPR抗体呈阳性,因此该研究提供了PPR疾病的死亡率和患病率与山羊高流产率的可能关联。

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