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Comparative Pathogenesis of Experimental Infections with Salmonella gallinarum in Local and Commercial Chickens

机译:鸡和地方鸡实验性鸡沙门氏菌感染的比较发病机理

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摘要

The pathogenicity of a virulent strain of Salmonella gallinarum was studied in local chickens and commercial layers. Sixty 4-month-old chickens were used. Of these, 50 chickens were orally infected with S. gallinarum, comprising 25 commercial layers and 25 local chickens. Five chickens in each group were used as uninfected negative controls. The clinical signs and pathological features of acute, subacute and chronic fowl typhoid were observed in both groups. Chickens in both groups seroconverted, but the antibody titre was significantly higher (p<0.001) in the commercial layers. The antibody titre remained high to the end of the experiment in all the surviving chickens. Only one commercial layer chicken died during the course of the experiment. The PCV decreased significantly (p<0.001) in the infected chickens of both groups as compared to the controls. The viable cell count of S. gallinarum in the liver and spleen reached a maximum on day 9 after infection in both groups. However, there was a significantly higher cell count (p<0.05) in the commercial layers. The severity of the disease appeared to be slightly greater in the commercial layers, although the susceptibility was similar in both groups. It was concluded that, under experimental conditions, local chickens are just as susceptible to S. gallinarum infection as are commercial layers.
机译:在当地鸡和商业鸡场中研究了鸡沙门氏菌的强毒株的致病性。使用了60只4个月大的鸡。其中,有50只鸡经口感染鸡毒链球菌,包括25头商业鸡和25头本地鸡。每组五只鸡用作未感染的阴性对照。两组均观察到急性,亚急性和慢性禽伤寒的临床体征和病理特征。两组鸡均发生血清转化,但在商业鸡中抗体滴度明显更高(p <0.001)。在所有存活的鸡中,抗体滴度一直很高,直到实验结束。在实验过程中,只有一只商业蛋鸡死亡。与对照组相比,两组感染鸡的PCV均显着降低(p <0.001)。两组感染后第9天,肝脏和脾脏中鸡链球菌的活细胞计数达到最大值。但是,商业层中的细胞数明显更高(p <0.05)。尽管两组的易感性相似,但在商业层面该疾病的严重程度似乎略高。结论是,在实验条件下,本地鸡与商业鸡一样容易感染鸡毒链球菌。

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  • 来源
    《Tropical Animal Health and Production》 |2002年第3期|195-204|共10页
  • 作者单位

    Department of Veterinary Medicine and Public Health Sokoine University of Agriculture;

    Department of Veterinary Medicine and Public Health Sokoine University of Agriculture;

    Department of Veterinary Medicine and Public Health Sokoine University of Agriculture;

    Department of Veterinary Microbiology and Parasitology Sokoine University of Agriculture;

    Department of Veterinary Medicine and Public Health Sokoine University of Agriculture;

    Department of Veterinary Microbiology and Parasitology Sokoine University of Agriculture;

    Department of Veterinary Microbiology The Royal Veterinary and Agricultural University;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    agglutination; antibody; breed; chickens; Salmonella gallinarum; PCV; resistance;

    机译:凝集;抗体;品种;鸡;鸡沙门氏菌;PCV;抗性;

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