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An Outbreak of Respiratory Disease Complex in Sheep in Central Ethiopia

机译:埃塞俄比亚中部绵羊爆发呼吸系统疾病综合症

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An investigation was carried out into an outbreak of respiratory disease complex (RDC) in 3641 Menz and Awassi×Menz cross sheep in Central Ethiopia between 1998 and 1999 by clinical, serological, microbiological, post-mortem and histopathological examinations. The monthly incidence of RDC varied from 2.8% to 4.0% and the prevalence was as high as 17%. The case fatality rate was 18%, despite culling of sick sheep. Over 76% of the morbidity occurred in adults, followed by 19% among weaners. Similarly, 62% of the mortality was in adults. However, 27% of the mortality occurred in lambs despite the low morbidity in the group. Significant breed and age differences were seen in the morbidity and mortality rates (p<0.05). Clinical signs, gross and microscopic lesions and serological and bacteriological examinations showed an interplay of several causes of the RDC, including pestes des petits ruminants (PPR) (72.3%, serologically confirmed), lung worms, maedi-visna, bacterial bronchopneumonia (staphylococcal and streptococcal), enzootic pneumonia and some fungal infections. Cold temperatures, which may be as low as –8.5°C at night, are major predisposing factors along with managemental stresses. Vaccination of animals with a homologous PPR vaccine appeared to decrease dramatically the occurrence of the disease, showing that PPR played an important role in the outbreak. Several of the pathogens do not appear to be individually capable of causing the respiratory disease. Appropriate strategies for the prevention of RDC are suggested.
机译:通过临床,血清学,微生物学,验尸和组织病理学检查,对1998年至1999年期间埃塞俄比亚中部3641名Menz和Awassi×Menz杂交绵羊的呼吸道疾病综合症(RDC)暴发进行了调查。 RDC的每月发生率从2.8%到4.0%不等,患病率高达17%。尽管淘汰了病羊,但病死率仍为18%。超过76%的发病率发生在成年人中,其次是在断奶仔猪中占19%。同样,死亡率的62%是成年人。然而,尽管该组发病率较低,但仍有27%的死亡率发生在羔羊身上。在发病率和死亡率上观察到显着的品种和年龄差异(p <0.05)。临床体征,肉眼和微观病变以及血清学和细菌学检查表明,RDC的多种原因相互影响,包括小反刍兽疫(PPR)(72.3%,经血清学确诊),蠕虫,前夜-visna,细菌性支气管肺炎(葡萄球菌和链球菌),动物性肺炎和一些真菌感染。晚上可能高达–8.5°C的低温是造成管理压力的主要诱因。用同源的PPR疫苗对动物进行疫苗接种似乎大大减少了疾病的发生,表明PPR在疫情爆发中发挥了重要作用。几种病原体似乎不能单独引起呼吸系统疾病。建议采取适当的策略预防RDC。

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