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首页> 外文期刊>Updates in Surgery >Objective outcomes of extra-esophageal symptoms following laparoscopic total fundoplication by means of combined multichannel intraluminal impedance pH-metry before and after surgery
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Objective outcomes of extra-esophageal symptoms following laparoscopic total fundoplication by means of combined multichannel intraluminal impedance pH-metry before and after surgery

机译：手术前后通过联合多通道腔内阻抗pH测定法对腹腔镜全胃底折叠术后食管外症状的客观结果

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Identifying and treating patients with extra-esophageal symptoms is a challenge. When the patient is unable to control his symptoms with pharmacological therapy alone, anti-reflux surgery may be indicated. This study aims to evaluate the outcomes of total fundoplication in the resolution of extra-esophageal manifestations and verify changes in 24-h MII-pH monitoring before and after surgery. From October 2005 to October 2010, patients who reported respiratory symptoms, possibly related to GERD, have been sent to our Institute. All patients were practiced ambulatory 24-h MII-pH before and after surgery. Thirty-five patients selected for the antireflux surgery have undergone all the same surgical procedures. Data were collected prospectively at 6 and 12 months after laparoscopic fundoplication. After laparoscopic fundoplication, the total percentage of exposure time with esophageal pH < 4, and both in upright and supine position was very low. A statistically significant difference (p < 0.05) was found in the number of detected refluxes at MII and detected refluxes at MII 15-cm segment in pre and post-operative period. Symptom relief was obtained in all patients. Laparoscopic fundoplication is a safe and effective procedure to protect from refractory GERD and extra-esophageal symptoms, when evaluated with a thorough pre-operative selection.
机译：识别和治疗食管外症状患者是一项挑战。如果患者仅靠药物治疗无法控制症状，则可能需要进行抗返流手术。这项研究旨在评估食管外表现的解决过程中全胃底折叠术的结果，并验证手术前后24小时MII-pH监测的变化。从2005年10月到2010年10月，报告可能与GERD相关的呼吸道症状的患者已被送往我们研究所。所有患者在手术前后均进行了24小时动态MII-pH训练。选择进行抗反流手术的35位患者均接受了所有相同的手术程序。前瞻性收集腹腔镜胃底折叠术后6和12个月的数据。腹腔镜胃底折叠术后，食管pH <4以及直立和仰卧位置的总暴露时间百分比非常低。术前和术后MII和MII 15厘米节段的返流数在统计学上有显着差异（p <0.05）。所有患者均获得症状缓解。进行彻底的术前选择评估时，腹腔镜胃底折叠术是一种安全有效的方法，可预防难治性GERD和食管外症状。

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