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首页> 外文期刊>Wiener klinische Wochenschrift >Schlafbezogene Atmungsst?rungen und maligne ventrikul?re Arrhythmien bei Patienten mit chronischer Herzinsuffizienz
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Schlafbezogene Atmungsst?rungen und maligne ventrikul?re Arrhythmien bei Patienten mit chronischer Herzinsuffizienz

机译:慢性心力衰竭患者与睡眠有关的呼吸障碍和恶性室性心律失常

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BACKGROUND: Patients with chronic heart failure (CHF) have a high incidence of sleep disordered breathing (SDB). It is assumed that patients with the combination of CHF and SDB have more ventricular couplets and nonsustained ventricular tachycardia (NSVT) than patients without SDB. METHODS: In 63 patients, 49 men and 14 women with chronic heart failure (EF < 45%), all-night polysomnography and long-term-ECG were performed. Mean age was 59 ± 15 years, mean BMI 27 ± 5 kg/m2. 56% had an ischemic, 44% a nonischemic heart disease. 51% had heart insufficiency classification NYHA III. RESULTS: 42 of the 63 patients (67%) had sleep disordered breathing (SDB) with an AHI ≥5/h. In 24 patients (38%) SDB was central, in 18 (29%) obstructive. More patients with SDB than patients without SDB had NSVT (50% vs. 19%). Nocturnal frequency of NSVT in patients with SDB was about twice as high as the rate observed during daytime (0.48/h vs. 0.21/h). In patients without SDB there was no relevant difference between day and night (0.23/h vs. 0.21/h). AHI correlated with NSVT (r = 0.329, p < 0.01). Dayight comparison of couplets was 2.3/h vs. 1.9/h in SDB patients and 2.0/h vs. 1.6/h in patients without SDB. CONCLUSIONS: Patients with chronic heart failure have a high prevalence of SDB. The combination of CHF and SDB predisposes for nocturnal malignant ventricular arrhythmias.
机译:背景:患有慢性心力衰竭(CHF)的患者睡眠呼吸障碍(SDB)的发生率很高。假设CHF和SDB合并的患者比没有SDB的患者具有更多的室联和非持续性室性心动过速(NSVT)。方法:对63例慢性心力衰竭(EF <45%)的49例男性和14例女性进行了整夜的多导睡眠监测和长期心电图检查。平均年龄为59±15岁,平均BMI为27±5 kg / m2 。 56%患有缺血性心脏病,44%患有非缺血性心脏病。 51%的患者有心脏功能不全分类NYHA III。结果:63名患者中有42名(67%)的睡眠呼吸障碍(SDB)的AHI≥5/ h。在24例患者(38%)中,SDB为中心性,在18例(29%)为阻塞性。与没有SDB的NSVT患者相比,患有SDB的患者更多(50%比19%)。 SDB患者的NSVT夜间频率大约是白天的两倍(0.48 / h对0.21 / h)。在没有SDB的患者中,昼夜之间没有相关差异(0.23 / h与0.21 / h)。 AHI与NSVT相关(r = 0.329,p <0.01)。白天/晚上的对联比较是SDB患者为2.3 / h vs.1.9 / h,而无SDB患者为2.0 / h vs.1.6 / h。结论:慢性心力衰竭患者的SDB患病率很高。 CHF和SDB的结合易诱发夜间恶性室性心律失常。

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