Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from baker's yeast by anions

C. Cennamo; G. Bonaretti; G. Montecuccoli; L. Razzoli

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Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from baker's yeast by anions

机译：阴离子对贝克酵母抑制烟酰胺 - 腺嘌呤二核苷酸特异性异柠檬酸脱氢酶的影响

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p1. The sensitivity of the NADsup+/sup-specific isocitrate dehydrogenase from baker9s yeast towards inhibition by anions decreases with decrease in pH. The patterns of the pH-dependence of the enzymic activity can be explained by this effect. 2. In the presence of a high isocitrate concentration, citrate, unlike AMP, has no antagonizing effect on the inhibition of the enzyme by anions. In the presence of AMP, citrate inhibits the enzyme at high isocitrate concentration and activates at low isocitrate concentration. 3. The effects on the enzymic activity of the previous incubation of the enzyme were studied in relation to the substrate concentration, the chloride concentration and the presence of citrate and AMP./p

机译：> 1。 NAD + / sup>的敏感性来自Baker9s酵母对阴离子的抑制作用的敏感性酶随着pH的降低而降低。可以通过这种效果解释酶活性的pH依赖性的模式。在存在高异柠檬酸浓度的情况下，与放大器不同，柠檬酸盐对阴离子抑制酶无拮抗作用。在AMP存在下，柠檬酸盐在高异亚硝酸盐浓度下抑制酶，并在低异亚硝酸盐浓度下活化。 3.研究了对酶的先前孵育的酶活性的影响与底物浓度，氯化物浓度和柠檬酸盐的存在相关。

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《The biochemical journal》 |1968年第3期|共页
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C. Cennamo; G. Bonaretti; G. Montecuccoli; L. Razzoli;
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收录信息美国《科学引文索引》(SCI);
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1. Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from baker's yeast by anions [J] . C. Cennamo, G. Bonaretti, G. Montecuccoli, The biochemical journal . 1968,第3期

机译：阴离子对贝克酵母抑制烟酰胺 - 腺嘌呤二核苷酸特异性异柠檬酸脱氢酶的影响
2. Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from baker's yeast by anions [J] . C. Cennamo, G. Bonaretti, G. Montecuccoli, The biochemical journal . 1968,第3期

机译：阴离子对贝克酵母抑制烟酰胺 - 腺嘌呤二核苷酸特异性异柠檬酸脱氢酶的影响
3. The effects of pH and citrate on the activity of nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria [J] . D. D. Davies, G. F. Cox The biochemical journal . 1969,第5期

机译：pH和柠檬酸盐对豌豆线粒体烟酰胺-腺嘌呤二核苷酸特异性异柠檬酸脱氢酶活性的影响
4. Preparation of Nicotinamide Adenine Dinucleotide Functionalized Multi-Walled Carbon Nanotube and Its Application to Dehydrogenase Biosensor [C] . Xingsheng Wang, Pu Liu, Haitao Zheng, International Conference on Soft Magnetic Materials . 2011

机译：烟酰胺腺嘌呤二核苷酸官能化多壁碳纳米管的制备及其在脱氢酶生物传感器的应用
5. Molecular systematics of Lipotyphla (Mammalia): Evidence from the mitochondrial genes 12S ribosomal RNA (12S rRNA) and nicotinamide adenine dinucleotide dehydrogenase subunit 2 (ND2). [D] . Emerson, Ginny Leigh. 2002

机译：Lipotyphla（哺乳动物）的分子系统：来自线粒体基因12S核糖体RNA（12S rRNA）和烟酰胺腺嘌呤二核苷酸脱氢酶亚基2（ND2）的证据。
6. Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from bakers yeast by anions [O] . C. Cennamo, G. Montecuccoli, G. Bonaretti, 1968

机译：pH值对阴离子抑制面包酵母烟酰胺-腺嘌呤二核苷酸特异性异柠檬酸脱氢酶的影响
7. Nicotinamide-adenine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria. [O] . Cox, G F, Davies, D D 1967

机译：来自豌豆线粒体的烟酰胺-腺嘌呤二核苷酸特异性异柠檬酸脱氢酶。
8. Phosphoribulokinase from 'Nitrobacter winogradskyi': Activation by Reduced Nicotinamide Adenine Dinucleotide and Inhibition by Pyridoxal Phosphate. [R] . Kiesow, L. A., Lindsley, B. F., Bless, J. W. 1976

机译：来自'Nitrobacter winogradskyi'的磷酸核糖激酶：通过还原的烟酰胺腺嘌呤二核苷酸激活和磷酸吡哆醛的抑制。

Effect of pH on the inhibition of the nicotinamide–adenine dinucleotide-specific isocitrate dehydrogenase from baker's yeast by anions

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