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Host-Cell Lysosomal Response to Two Strains of Herpes Simplex Virus

机译:宿主细胞溶酶体反应两种单纯疱疹病毒

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A correlation has been made between the host lysosomal responses to and release of infectious virus from HEp-2 cells infected with two strains of herpes simplex virus (HSV). Supravital staining with acridine orange was used for morphological studies of macroplaque and microplaque HSV-infected cells. With the progression of infection, cells infected with either microplaque HSV or macroplaque HSV were observed to undergo different lysosomal and cytopathic changes, which could be correlated with increased accumulation of acid phosphatase and infectious virus in the extracellular fluid.
机译:来自Hep-2细胞的宿主溶酶体反应和释放感染的HEP-2细胞之间的相关性,其具有两种疱疹病毒(HSV)的HEP-2细胞。用吖啶橙色染色染色用于宏观测量和微量HSV感染细胞的形态学研究。随着感染的进展,观察到用微量化HSV或大甲基汞HSV感染的细胞进行不同的溶酶体和细胞病变变化,这可以与细胞外液中的酸性磷酸酶和传染病的增加增加。

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