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Cell-wall Constituents of Rickettsiae and Psittacosis-Lymphogranuloma Organisms

机译:Rickettsiae和Psittacisis-淋巴甘油瘤生物的细胞壁成分

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SUMMARY: The taxonomic position of organisms belonging to the rickettsiae and psittacosis-lymphogranuloma groups is controversial. Although, like viruses, all pathogenic forms of these organisms are obligate intracellular parasites, in other respects they resemble bacteria. Since a cell wall, deriving its rigidity from mucopeptide, which contains the amino sugar muramic acid as a key constituent, has so far only been found in bacteria and the closely related blue-green algae, the presence of muramic acid in an organism may be used as a taxonomic criterion. The mucopeptides of bacterial cell walls are also often sensitive to lysozyme, so that dissolution by this enzyme serves as an indication of the presence of mucopeptide. Organisms of the rickettsiae and psittacosis-lymphogranuloma groups have been examined for the presence of muramic acid. Critical chemical tests have shown that this substance is present in organisms of both groups. Cell walls of Rickettsia burnetii were dissolved by lysozyme. In the light of these and other results the taxonomic position of these groups of organisms is discussed.
机译:摘要:属于Rickettsiae和Psittacisis-淋巴甘油瘤组的生物的分类立场是有争议的。虽然如病毒,但这些生物的所有致病形式都是在其他对细菌的其他方面的细胞内寄生虫。由于含有含有氨基肽的粘膜肽作为关键成分的细胞壁,因此只发现了细菌和密切相关的蓝绿藻,因此有机体中的蛋白酸存在的存在用作分类标准。细菌细胞壁的粘液肽也经常对溶菌酶敏感,因此通过该酶的溶解用作粘肽存在的指示。已经检查了Rickettsiae和Psittaciss-淋巴细胞瘤组的生物体用于蛋白酸的存在。关键化学试验表明,这种物质存在于两组的生物中。用溶菌酶溶解Ricteetsia Burnetii的细胞壁。鉴于这些和​​其他结果,讨论了这些生物组的分类物理位置。

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