• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Virology >Characterization of temperature-sensitive mutants of simian rotavirus SA11: protein synthesis and morphogenesis.
【24h】

Characterization of temperature-sensitive mutants of simian rotavirus SA11: protein synthesis and morphogenesis.

机译：Simian Rotavirus SA11的温度敏感突变体的表征：蛋白质合成和形态发生。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The synthesis of viral polypeptides, distribution of viral antigens, and morphogenesis of viral structures have been examined in cells infected with temperature-sensitive (ts) mutants of SA11 representing 10 recombination groups. At the permissive temperature (31 degrees C) the synthesis of viral polypeptides and the distribution of viral antigens did not differ significantly from those of the wild type. At the nonpermissive temperature (39 degrees C) some mutants (tsB, -C, -E, -F, and -G) synthesized significantly smaller amounts of viral polypeptides and had a very diffuse distribution of viral antigen. Several of the mutants synthesized one or more electrophoretically aberrant polypeptide species at both 31 and 39 degrees C. All of the mutants, except tsF, assembled morphogenetic intermediates at 39 degrees C. Aberrant intermediates were assembled in all mutants at 31 and 39 degrees C. No specific morphogenic defect could be associated with any of the ts mutants.
机译：病毒多肽的合成，病毒抗原的分布，以及病毒结构的形态发生，在感染的细胞中，在SA11的温度敏感（TS）突变体的细胞中，代表10个重组基团。在允许温度（31摄氏度）在野生型中的病毒多肽的合成和病毒抗原的分布没有显着差异。在非智能温度（39℃）的情况下，一些突变体（TSB，-C，-E，-F和-G）合成显着较少的病毒多肽，并且具有非常漫反射的病毒抗原分布。几个突变体在31和39℃下合成一种或多种电泳异常多肽物质。除了TSF的所有突变体，在39℃下组装在39℃的形态发生中间体。在31和39℃的所有突变体中组装在所有突变体中。没有特异的形态发生缺损可以与任何TS突变体相关联。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号