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Antibody-independent detection of virus-specific glycoprotein synthesis is oncornavirus-infected cells.

机译:抗体无关检测病毒特异性糖蛋白合成是oncornavirus感染的细胞。

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摘要

A method is described for detecting the synthesis of avian and murine oncornavirus-specific glycoproteins without the use of antibodies raised against viral structural proteins. As applied to cells infected with avian tumor virus, the method served to resolve pr90, the precursor of the major envelope glycoprotein. A virus-specific glycoprotein of about 85,000 daltons, which has several properties expected to a precursor to gp69/71, was detected in cells infected with murine leukemia virus.
机译:描述了一种方法,用于检测禽类和鼠Oncornavirus特异性糖蛋白的合成而不使用针对病毒结构蛋白的抗体的合成。如应用于感染禽肿瘤病毒的细胞,该方法用于分解PR90,主要包膜糖蛋白的前体。在感染鼠白血病病毒感染的细胞中检测到预期对GP69 / 71的前体预期的若干特性的病毒特异性糖蛋白。

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