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Turtle-dove ovomucoid, a glycoprotein proteinase inhibitor with P1-blood-group antigen activity

机译:Turtle-Dove Ovomucoid,一种糖蛋白蛋白酶抑制剂,具有P1血群抗原活性

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pOvomucoid from the egg white of turtle-dove (Streptopelia risoria) was purified and shown to be a glycoprotein of mol. wt. 29 400, with valine as N-terminal residue. It is an inhibitor of both trypsin and chymotrypsin, but has a lower affinity for trypsin than has hen ovomucoid. Turtle-dove ovomucoid contains antigenic activity cross-reacting with the blood-group-P1 antigen of human erythrocytes. Hen ovomucoid has no detectable blood group-P1 activity. The carbohydrate composition of turtle-dove ovomucoid differs from hen ovomucoid in having substantially higher galactose content. The possible relationship between carbohydrate composition and antigenic activity is discussed./p
机译:>从龟豚(Streptopelia risoria)的蛋白蛋饼被纯化并显示为摩尔蛋白。 wt。 29 400,用缬氨酸作为N-末端残留物。它是胰蛋白酶和胰蛋白酶的抑制剂,但对胰蛋白酶的亲和力较低而不是荨麻酸。龟豚鼠卵巢含有与人红细胞的血液组-P1抗原交叉反应的抗原活性。 Hen Ovomucoid没有可检测的血液组-P1活性。龟叶卵状酸的碳水化合物组合物与母鸡卵琥珀酸的不同之处在于具有基本上更高的半乳糖含量。讨论了碳水化合物组成和抗原活性之间的可能关系。

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