High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins.

J E Alouf; C Geoffroy; D Klatzmann; J C Gluckman; J Gruest; L Montagnier

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High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins.

机译：通过被链球菌促毒素刺激的人T淋巴细胞高产生所得免疫缺陷综合征病毒（淋巴结病相关病毒）。

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Purified streptococcal mitogens (SMs) including erythrogenic exotoxin were compared with phytohemagglutinin (PHA) for their ability to sustain lymphadenopathy-associated virus (LAV) replication after the stimulation of normal human peripheral blood mononuclear cells and purified CD4+ and CD8+ T cells infected with LAV. Both SM and PHA supported LAV production in peripheral blood mononuclear and CD4+ cells but not in CD8+ cells. LAV production assessed by the assay of reverse transcriptase in cell supernatants appeared earlier after stimulation with SM and was 6- to 10-fold greater than after stimulation by PHA.

机译：将纯化的链球菌丝酮（SMS）与植物葡萄球菌（PHA）进行比较，以便在刺激正常人外周血单核细胞并纯化CD4 +和CD8 + T细胞后维持淋巴结病相关病毒（LAV）复制的能力。 SM和PHA都支持外周血单核和CD4 +细胞的LAV生产，但不在CD8 +细胞中。通过在细胞上清液中的逆转录酶的测定评估的LAV生产在用SM刺激后之前出现，并且比PHA的刺激后6至10倍。

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《Journal of Clinical Microbiology》 |1986年第4期|共3页
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J E Alouf; C Geoffroy; D Klatzmann; J C Gluckman; J Gruest; L Montagnier;
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1. High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins. [J] . J E Alouf, C Geoffroy, D Klatzmann, Journal of Clinical Microbiology . 1986,第4期

机译：通过被链球菌促毒素刺激的人T淋巴细胞高产生所得免疫缺陷综合征病毒（淋巴结病相关病毒）。
2. High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins. [J] . J E Alouf, C Geoffroy, D Klatzmann, Journal of Clinical Microbiology . 1986,第期

机译：通过被链球菌促毒素刺激的人T淋巴细胞高产生所得免疫缺陷综合征病毒（淋巴结病相关病毒）。
3. Detection and differentiation by sandwich enzyme-linked immunosorbent assay of human T-cell lymphotropic virus type III/lymphadenopathy-associated virus- and acquired immunodeficiency syndrome-associated retroviruslike clinical isolates. [J] . J R Higgins, N C Pedersen, J R Carlson Journal of Clinical Microbiology . 1986,第3期

机译：通过夹心酶联免疫吸附法检测和区分人类T细胞淋巴病毒III型/淋巴结病相关病毒和获得性免疫缺陷综合症相关逆转录病毒样临床分离株。
4. Prevalence and related factors of anemia among human immunodeficiency virus(HIV)/acquired immune deficiency syndrome (AIDS) outpatients in resources limited region of China [C] . Zhibin Liu, Yantao Jin, Jiping Yang, IEEE International Conference on Bioinformatics and Biomedicine . 2013

机译：资源有限地区人类免疫缺陷病毒（HIV）/后天免疫缺陷综合症（AIDS）门诊患者贫血患病率及相关因素
5. Assessing knowledge, attitude, behavior, and practices related to Human Immunodeficiency Virus infection and Acquired Immunodeficiency Syndrome in a United States-based refugee population. [D] . Munene, Esther N. 2012

机译：评估以美国为基地的难民人口中与人类免疫缺陷病毒感染和后天免疫缺陷综合症有关的知识，态度，行为和做法。
6. High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins. [O] . J E Alouf, C Geoffroy, D Klatzmann, 1986

机译：链球菌有丝分裂毒素刺激的人T淋巴细胞高产获得性免疫缺陷综合症病毒（淋巴结病相关病毒）。
7. High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins [O] . J E Alouf, C Geoffroy, D Klatzmann, 1986

机译：通过被链球菌促毒素刺激的人T淋巴细胞高生产可获得的免疫缺陷综合征病毒（淋巴结病相关病毒）
8. CDC Guidelines for National Human Immunodeficiency Virus Case Surveillance,211 Including Monitoring for Human Immunodeficiency Virus Infection and Acquired 211 Immunodeficiency Syndrome. Morbidity and Mortality Weekly Report, Vol. 48, No. RR-211 13, Decem [R] . Fleming, P. L., Ward, J. W., Janssen, R. S., 1999

机译：疾病预防控制中心国家人体免疫缺陷病毒病例监测指南，211包括人类免疫缺陷病毒感染监测和获得性免疫缺陷综合症。发病率和死亡率周报，Vol。 48，编号RR-211 13，Decem

High production of the acquired immunodeficiency syndrome virus (lymphadenopathy-associated virus) by human T lymphocytes stimulated by streptococcal mitogenic toxins.

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