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首页> 外文期刊>Water Research >Reaction of chlorine dioxide with emergent water pollutants: Product study of the reaction of three β-lactam antibiotics with ClO_2
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Reaction of chlorine dioxide with emergent water pollutants: Product study of the reaction of three β-lactam antibiotics with ClO_2

机译:二氧化氯与水污染物的反应:三种β-内酰胺类抗生素与ClO_2反应的产物研究

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摘要

This work deals with the chlorine dioxide (ClO_2) reactivity with three representative /f-lactam antibiotics (penicillin, amoxicillin and cefadroxil) that can be present in natural aquatic resources. Due to the wide use of ClO_2 as disinfection agent our work is of interest to determine the fate of these antibiotics during the water treatment process. Our study shows that antibiotics react stoichiometrically with ClO_2 because increasing amounts of ClO_2 lead to increasing antibiotic disappearance. Concerning the influence of antibiotic structure, penicillin reacts sluggishly with ClO_2, whereas amoxicillin and cefadroxil are highly reactive at either neutral or basic pH. For both reactive antibiotics, hydroquinone together with a wide range of 4-substituted phenols were detected as products. Pretreatment with ClO_2 before chlorination of aqueous solutions of antibiotics reduces the trihalomethane formation as compared with analogous chlorination without ClO_2 pretreatment.
机译:这项工作涉及天然水生资源中可能存在的三种代表性的/ f-内酰胺类抗生素(青霉素,阿莫西林和头孢氨苄)的二氧化氯(ClO_2)反应性。由于ClO_2作为消毒剂的广泛应用,我们的工作对于确定这些抗生素在水处理过程中的命运很有意义。我们的研究表明,抗生素与ClO_2发生化学计量反应,因为ClO_2的增加导致抗生素消失的增加。关于抗生素结构的影响,青霉素与ClO_2反应缓慢,而阿莫西林和头孢羟氨苄在中性或碱性pH下均具有高反应性。对于这两种反应性抗生素,均检测到氢醌与多种4-取代酚一起作为产物。与未经ClO_2预处理的类似氯化相比,在将抗生素水溶液氯化之前用ClO_2进行的预处理减少了三卤甲烷的形成。

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