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RSC Medicinal Chemistry

中文名称：RSC药物化学

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1.Design, synthesis, and biological evaluation of indole-modified tamoxifen relatives as potent anticancer agents

机译：Design, synthesis, and biological evaluation of indole-modified tamoxifen relatives as potent anticancer agents
- 作者：Ertugrul Berrak;Aytatli Abdulmelik;Karatas Omer FarukSaracoglu Nurullah
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
- ESTROGEN-RECEPTOR MODULATORS;
- BREAST-CANCER;
- PROLIFERATION;
- ALKALOIDS;
- IDENTIFICATION;
- ANTIESTROGENS;
- RESISTANCE;
- BACTERIUM;
- GREB1;
2.Integrating a covalent probe with ubiquicidin fragment enables effective bacterial infection imaging

机译：Integrating a covalent probe with ubiquicidin fragment enables effective bacterial infection imaging
- 作者：Mitra Jyotsna Bhatt;Chatterjee Saurav;Kumar AnujBandyopadhyay AnupamMukherjee Archana
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第10期
- TC-99M-UBIQUICIDIN 29-41;
- CLINICAL UTILITY;
- MEMBRANE;
- PEPTIDE;
3.Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties

机译：Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties
- 作者：de Andrade Ramos Giselle;Souza de Oliveira Andressa;Bartolini ManuelaNaldi MarinaLiparulo IreneBergamini ChristianUliassi ElisaWu LingFraser Paul E.Abreu MonicaKiametis Alessandra SofiaGargano RicardoSilveira Edilberto RochaBrand Guilherme D.Prchal LukasSoukup OndrejKorabecny JanBolognesi Maria LauraSoares Romeiro Luiz Antonio
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第7期
4.Antibacterial activities of anthraquinones: structure–activity relationships and action mechanisms

机译：Antibacterial activities of anthraquinones: structure–activity relationships and action mechanisms
- 作者：Qun Tang;Zhou Tiantian;Hao JiongkaiWang ChunmeiZhang KeyuXu JingWang XiaoyangZhou Wen
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
5.First-in-class small molecule inhibitors of ICOS/ICOSL interaction as a novel class of immunomodulators

机译：First-in-class small molecule inhibitors of ICOS/ICOSL interaction as a novel class of immunomodulators
- 作者：Abdel-Rahman Somaya A.;Swiderek Katarzyna;Gabr Moustafa T.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- REGULATORY T-CELLS;
- PLASMACYTOID DENDRITIC CELLS;
- ICOS-LIGAND;
- INDUCIBLE COSTIMULATOR;
- FORCE-FIELD;
- CANCER;
- DYNAMICS;
- ANTIBODY;
- SOFTWARE;
- IMMUNOSUPPRESSION;
6.Thiourea derivatives containing 4-arylthiazoles and D-glucose moiety: design, synthesis, antimicrobial activity evaluation, and molecular docking/dynamics simulations

机译：Thiourea derivatives containing 4-arylthiazoles and D-glucose moiety: design, synthesis, antimicrobial activity evaluation, and molecular docking/dynamics simulations
- 作者：Thanh Nguyen Dinh;Lan Pham Hong;Hai Do SonAnh Hoang HuuGiang Nguyen Thi KimVan Hoang Thi KimToan Vu NgocTri Nguyen MinhToan Duong Ngoc
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- THIAZOLE;
- ANTIBACTERIAL;
- INHIBITORS;
- ANTIFUNGAL;
7.Research progress of anticancer drugs targeting CDK12

机译：Research progress of anticancer drugs targeting CDK12
- 作者：Yan Zhijia;Du Yongli;Zhang HaibinZheng YongLv HuitingDong NingHe Fang
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- PROTEIN-DEGRADATION;
- KINASE;
- CANCER;
- EXPRESSION;
- INHIBITORS;
- RESISTANCE;
- DISCOVERY;
- REPAIR;
- POTENT;
- GENES;
8.Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds

机译：Enhancing allosteric inhibition of dihydrodipicolinate synthase through the design and synthesis of novel dimeric compounds
- 作者：Christoff Rebecca M.;Al Bayer Mohammad;Soares da Costa Tatiana P.Perugini Matthew A.Abbott Belinda M.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
9.Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors

机译：Design, synthesis and biological evaluation of light-driven on-off multitarget AChE and MAO-B inhibitors
- 作者：Paolino Marco;Rullo Mariagrazia;Maramai Samuelede Candia ModestoPisani LeonardoCatto MarcoMugnaini ClaudiaBrizzi AntonellaCappelli AndreaOlivucci MassimoCorelli FedericoAltomare Cosimo D.
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第7期
- ACETYLCHOLINESTERASE INHIBITORS;
- PROTEIN;
- DERIVATIVES;
- TACRINE;
- DISEASE;
- LIGAND;
- INDANONE;
- EFFICACY;
- DOCKING;
- AGENTS;
10.Front cover

机译：Front cover
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
11.Synthesis, activity and metabolic stability of propan-2-one substituted tetrazolylalkanoic acids as dual inhibitors of cytosolic phospholipase A 2 alpha and fatty acid amide hydrolase

机译：Synthesis, activity and metabolic stability of propan-2-one substituted tetrazolylalkanoic acids as dual inhibitors of cytosolic phospholipase A 2 alpha and fatty acid amide hydrolase
- 作者：Voundi Merlin Ekodo;Hanekamp Walburga;Lehr Matthias
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- BIOLOGICAL-ACTIVITY;
- A(2);
- 1-INDOL-1-YL-PROPAN-2-ONES;
- DESIGN;
- HPLC;
12.Introduction to the antibiotic and antiviral compounds themed collection

机译：Introduction to the antibiotic and antiviral compounds themed collection
- 作者：Sofia Michael J.;Li Xuechen
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第9期
13.Design, synthesis, and evaluation of BTK-targeting PROTACs with optimized bioavailability in vitro and in vivo

机译：Design, synthesis, and evaluation of BTK-targeting PROTACs with optimized bioavailability in vitro and in vivo
- 作者：Sun Yonghui;Yang Zimo;Zhang ZhiminLi ZhenGuo LiubinPan HaoLuo XinLiu DongzhouRao Yu
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
14.CDK9 inhibitors in cancer research

机译：CDK9 inhibitors in cancer research
- 作者：Huang Zhi;Wang Tianqi;Wang ChengFan Yan
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第6期
15.Carborane clusters increase the potency of bis-substituted cyclam derivatives against Mycobacterium tuberculosis

机译：Carborane clusters increase the potency of bis-substituted cyclam derivatives against Mycobacterium tuberculosis
- 作者：Smith Nicholas;Quan Diana;Nagalingam GayathriTriccas James A.Rendina Louis M.Rutledge Peter J.
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第10期
- BORON;
- DECABORANE;
- DISCOVERY;
- AGENTS;
- ROUTE;
16.Chemical modulation of Kv7 potassium channels

机译：Chemical modulation of Kv7 potassium channels
- 作者：Borgini Matteo;Mondal Pravat;Liu RuitingWipf Peter
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第4期
17.Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators

机译：Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators
- 作者：Zhang Xujie;Sun Lin;Xu ShujingHuang TianguangZhao FabaoDing DangLiu ChuanfengJiang XiangyiTao YucenKang DongweiDe Clercq ErikPannecouque ChristopheCocklin SimonDick AlexejLiu XinyongZhan Peng
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
18.Detection of intact vancomycin-arginine as the active antibacterial conjugate in E. coli by whole-cell solid-state NMR

机译：Detection of intact vancomycin-arginine as the active antibacterial conjugate in E. coli by whole-cell solid-state NMR
- 作者：Werby Sabrina H.;Brcic Jasna;Chosy Madeline B.Sun JiuzhiRendell Jacob T.Neville Lewis F.Wender Paul A.Cegelski Lynette
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
19.Tackling antimicrobial stewardship through synergy and antimicrobial peptides

机译：Tackling antimicrobial stewardship through synergy and antimicrobial peptides
- 作者：Greve Jenna M.;Cowan James A.
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第5期
- QUORUM-SENSING INHIBITORS;
- PISCIDIN 3;
- RESISTANCE;
- MECHANISM;
- THERAPY;
- MODE;
- RIBONUCLEASE;
- COMBINATIONS;
- COPPER(II);
- STRATEGIES;
20.Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052

机译：Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052
- 作者：Kawagoe Fumihiro;Mototani Sayuri;Mendoza AileenTakemoto YasushiUesugi MotonariKittaka Atsushi
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- LIPID-METABOLISM;
- DERIVATIVES;
- ACTIVATION;
- RECEPTOR;
21.Hydroxypyrone derivatives in drug discovery: from chelation therapy to rational design of metalloenzyme inhibitors

机译：Hydroxypyrone derivatives in drug discovery: from chelation therapy to rational design of metalloenzyme inhibitors
- 作者：Arshad Jahan Zaib;Hanif Muhammad
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第10期
22.Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction

机译：Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction
- 作者：Mitry Madonna M. A.;Boateng Samuel Y.;Greco FrancescaOsborn Helen M. I.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
23.Synthesis and pharmacological evaluation of 1,3-diaryl substituted pyrazole based (thio)urea derivatives as potent antimicrobial agents against multi-drug resistant Staphylococcus aureus and Mycobacterium tuberculosis

机译：Synthesis and pharmacological evaluation of 1,3-diaryl substituted pyrazole based (thio)urea derivatives as potent antimicrobial agents against multi-drug resistant Staphylococcus aureus and Mycobacterium tuberculosis
- 作者：Ommi Ojaswitha;Ahmad Mohammad Naiyaz;Gajula Siva Nageswara RaoWanjari ParitaSau ShashikantaAgnivesh Puja KumariSahoo Santosh KumarKalia Nitin PalSonti RajeshNanduri SrinivasDasgupta ArunavaChopra SidharthYaddanapudi Venkata Madhavi
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
- DNA GYRASE INHIBITORS;
- ANTIBACTERIAL ACTIVITY;
- DESIGN;
- INFECTIONS;
- DISCOVERY;
- PROGRESS;
- UREAS;
24.Screening and optimization of phage display cyclic peptides against the WDR5 WBM site

机译：Screening and optimization of phage display cyclic peptides against the WDR5 WBM site
- 作者：Song Lingyu;Cao Jiawen;Chen LinDu ZhiyanZhang NaixiaCao DanyanXiong Bing
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- HISTONE H3;
- COMPLEX;
- RECOGNITION;
- CYCLIZATION;
- SCAFFOLDS;
- SELECTION;
- BINDING;
25.Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties

机译：Boron-based hybrids as novel scaffolds for the development of drugs with neuroprotective properties
- 作者：Cacciatore Ivana;Turkez Hasan;Di Rienzo AnnalisaCiulla MicheleMardinoglu AdilDi Stefano Antonio
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第11期
- ALZHEIMERS-DISEASE;
- LIPOIC ACID;
- ANTIOXIDANTS;
26.Comprehensive analysis of commercial fragment libraries

机译：Comprehensive analysis of commercial fragment libraries
- 作者：Imbernon Julia Revillo;Jacquemard Celien;Bret GuillaumeMarcou GillesKellenberger Esther
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第3期
- DRUG DISCOVERY;
- IMPACT;
- LEADS;
- RULE;
27.Introduction to the themed collection on antimicrobial resistance

机译：Introduction to the themed collection on antimicrobial resistance
- 作者：Haldar Jayanta;Garneau-Tsodikova Sylvie;Fridman Micha
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
28.Contents list

机译：Contents list
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
29.Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors

机译：Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors
- 作者：Kong Jiao;Long Ya-Qiu
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第3期
- SOMATIC PTPN11 MUTATIONS;
- NOONAN-SYNDROME;
- LEOPARD-SYNDROME;
- ALLOSTERIC INHIBITION;
- MOLECULAR-MECHANISM;
- CANCER;
- ACTIVATION;
- GENE;
- RAS;
- DIFFERENTIATION;
30.Identification of a new class of proteasome inhibitors based on a naphthyl-azotricyclic-urea-phenyl scaffold

机译：Identification of a new class of proteasome inhibitors based on a naphthyl-azotricyclic-urea-phenyl scaffold
- 作者：Allardyce Duncan;Adu Mantey Priscilla;Szalecka MonikaNkwo RobertLoizidou Eriketi Z.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第3期
- 20 S PROTEASOME;
- ACTIVE-SITES;
- IMMUNOPROTEASOME;
- DESIGN;
- SYSTEM;
- DISCOVERY;
- DOCKING;
- MODEL;
31.Identification of 2-arylquinazolines with alkyl-polyamine motifs as potent antileishmanial agents: synthesis and biological evaluation studies

机译：Identification of 2-arylquinazolines with alkyl-polyamine motifs as potent antileishmanial agents: synthesis and biological evaluation studies
- 作者：Kumari Anjila;Jaiswal Tara;Kumar VinayHura NehaKumar GulshanBabu Neerupudi KishoreAcharya AyanRoy Pradyot K.Guchhait Sankar K.Singh Sushma
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第3期
- QUINAZOLINE DERIVATIVES;
- MECHANISM;
- RESISTANCE;
- DISCOVERY;
- LIBRARIES;
- ANALOGS;
- PYBROP;
- ASSAY;
32.Current status and prospects of MIL-based MOF materials for biomedicine applications

机译：Current status and prospects of MIL-based MOF materials for biomedicine applications
- 作者：Lin Zengqin;Liao Donghui;Jiang ChenyiNezamzadeh-Ejhieh AlirezaZheng MinbinYuan HuiLiu JianqiangSong HailiangLu Chengyu
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- METAL-ORGANIC FRAMEWORKS;
- PHOTODYNAMIC THERAPY;
- DELIVERY SYSTEM;
- CANCER;
- PLATFORM;
- ENZYMES;
- IMMUNOTHERAPY;
- MECHANISMS;
- LIGHT;
33.Current status and prospects of MIL-based MOF materials for biomedicine applications

机译：Current status and prospects of MIL-based MOF materials for biomedicine applications
- 作者：Lin Zengqin;Liao Donghui;Jiang ChenyiNezamzadeh-Ejhieh AlirezaZheng MinbinYuan HuiLiu JianqiangSong HailiangLu Chengyu
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- METAL-ORGANIC FRAMEWORKS;
- PHOTODYNAMIC THERAPY;
- DELIVERY SYSTEM;
- CANCER;
- PLATFORM;
- ENZYMES;
- IMMUNOTHERAPY;
- MECHANISMS;
- LIGHT;
34.Synthesis and antibacterial activity of 2-benzylidene-3-oxobutanamide derivatives against resistant pathogens

机译：Synthesis and antibacterial activity of 2-benzylidene-3-oxobutanamide derivatives against resistant pathogens
- 作者：Sood Ankur;Kesavan Venkitasamy
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- CARE-ASSOCIATED INFECTIONS;
- ANTIBIOTIC-RESISTANCE;
- CHALCONES;
- PLATENSIMYCIN;
- METHICILLIN;
- DISCOVERY;
35.Novel 1,2,4-oxadiazole compounds as PPAR-α ligand agonists: a new strategy for the design of antitumour compounds

机译：Novel 1,2,4-oxadiazole compounds as PPAR-α ligand agonists: a new strategy for the design of antitumour compounds
- 作者：Apaza Ticona Luis;Sánchez Sánchez-Corral Javier;Flores Sepúlveda AlejandroSoriano Vázquez CarmenHernán Vieco CarmenRumbero Sánchez Ángel
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
36.Optimization of the 2-arylquinazoline-4( 3H )one scaffold for a selective and potent antitrypanosomal agent: modulation of the mechanism of action through chemical functionalization

机译：Optimization of the 2-arylquinazoline-4( 3H )one scaffold for a selective and potent antitrypanosomal agent: modulation of the mechanism of action through chemical functionalization
- 作者：Romero Angel H.;Aguilera Elena;Gotopo LourdesCabrera GustavoDavila BelenCerecetto Hugo
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- ANTILEISHMANIAL ACTIVITY;
- DIHYDROFOLATE-REDUCTASE;
- TRYPANOSOMA-CRUZI;
- DRUG DISCOVERY;
- LEISHMANIA;
- INHIBITORS;
- SERIES;
- CHEMOTHERAPY;
- DERIVATIVES;
- METABOLISM;
37.Structure-based discovery of potent inhibitors of Axl: design, synthesis, and biological evaluation

机译：Structure-based discovery of potent inhibitors of Axl: design, synthesis, and biological evaluation
- 作者：Wu Shuang;Liao Min;Li MinxiongSun MingmingXi NingZeng Youlin
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第10期
- RECEPTOR TYROSINE KINASES;
- CELL LUNG-CANCER;
- GENE;
- GROWTH;
- TARGET;
38.Small-molecule inhibitors of bacterial-producing metallo-beta-lactamases: insights into their resistance mechanisms and biochemical analyses of their activities

机译：Small-molecule inhibitors of bacterial-producing metallo-beta-lactamases: insights into their resistance mechanisms and biochemical analyses of their activities
- 作者：Ayipo Yusuf Oloruntoyin;Chong Chien Fung;Mordi Mohd Nizam
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- ESCHERICHIA-COLI;
- POTENT;
- SUSCEPTIBILITY;
- DISCOVERY;
- NDM-1;
39.Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn(ii), Co(ii) and Ni(ii) complexes - combined experimental and theoretical measurements towards DNA/BSA/SARS-CoV-2 3CL Pro

机译：Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn(ii), Co(ii) and Ni(ii) complexes - combined experimental and theoretical measurements towards DNA/BSA/SARS-CoV-2 3CL Pro
- 作者：Sakthikumar Karunganathan;Isamura Bienfait Kabuyaya;Krause Rui Werner Macedo
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
40.Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues

机译：Inhibition of transcription and antiproliferative effects in a cancer cell line using antigene oligonucleotides containing artificial nucleoside analogues
- 作者：Wang Lei;Notomi Ryotaro;Sasaki ShigekiTaniguchi Yosuke
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
41.4-Aminopyrazolopyrimidine scaffold and its deformation in the design of tyrosine and serine/threonine kinase inhibitors in medicinal chemistry

机译：4-Aminopyrazolopyrimidine scaffold and its deformation in the design of tyrosine and serine/threonine kinase inhibitors in medicinal chemistry
- 作者：Chen Xiaolu;Huang Yajiao;Xu WanghanCai YuepiaoYang Yuanrong
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第9期
- C-SRC KINASE;
- HIGHLY POTENT;
- SELECTIVE INHIBITOR;
- ANTITUMOR-ACTIVITY;
- DUAL INHIBITORS;
- BTK INHIBITORS;
- DISCOVERY;
- GROWTH;
- DERIVATIVES;
- PI3K-DELTA;
42.Front cover

机译：Front cover
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
43.Recent developments in membrane targeting antifungal agents to mitigate antifungal resistance

机译：Recent developments in membrane targeting antifungal agents to mitigate antifungal resistance
- 作者：Mehta Devashish;Saini Varsha;Bajaj Avinash
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
44.Back cover

机译：Back cover
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
45.Polysaccharides from marine biological resources and their anticancer activity on breast cancer

机译：Polysaccharides from marine biological resources and their anticancer activity on breast cancer
- 作者：Yang Shengfeng;Li Dacheng;Liu WeiliChen Xiaolin
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- MOLECULAR-WEIGHT FUCOIDAN;
- IN-VITRO;
- BROWN SEAWEEDS;
- SULFATED POLYSACCHARIDE;
- UNDARIA-PINNATIFIDA;
- FUCUS-VESICULOSUS;
- APOPTOSIS;
- CELLS;
- MDA-MB-231;
- INDUCTION;
46.Novel 1,2,4-oxadiazole compounds as PPAR-alpha ligand agonists: a new strategy for the design of antitumour compounds

机译：Novel 1,2,4-oxadiazole compounds as PPAR-alpha ligand agonists: a new strategy for the design of antitumour compounds
- 作者：Apaza Ticona Luis;Sanchez Sanchez-Corral Javier;Flores Sepulveda AlejandroSoriano Vazquez CarmenHernan Vieco CarmenRumbero Sanchez Angel
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
- PROLIFERATOR-ACTIVATED RECEPTOR;
- THIOPHENE;
- APOPTOSIS;
- TOXICITY;
47.STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction

机译：STING antagonists, synthesized via Povarov-Doebner type multicomponent reaction
- 作者：Ong Wilson W. S.;Dayal Neetu;Chaudhuri RiddhiLamptey JonesSintim Herman O. O.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- GMP-AMP SYNTHASE;
- INNATE IMMUNITY;
- DISCOVERY;
- CGAS;
48.Inside front cover

机译：Inside front cover
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
49.Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

机译：Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity
- 作者：De Luca Laura;Lombardo Lisa;Mirabile SalvatoreMarrazzo AgostinoDichiara MariaCosentino GiuseppeAmata EmanueleGitto Rosaria
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- MEDICINAL CHEMISTRY;
- PROTEIN;
- LIGANDS;
- INSIGHTS;
- TARGETS;
- MODEL;
50.Natural-product-based fluorescent probes: recent advances and applications

机译：Natural-product-based fluorescent probes: recent advances and applications
- 作者：Sung Dan-Bi;Lee Jong Seok
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第3期
51.Covalent drugs targeting histidine - an unexploited opportunity?

机译：Covalent drugs targeting histidine - an unexploited opportunity?
- 作者：Che Jianwei;Jones Lyn H.
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第10期
- SULFONYL FLUORIDES;
- CHEMICAL PROTEOMICS;
- INHIBITORS;
- SITE;
- IDENTIFICATION;
- LENALIDOMIDE;
- ESTERASES;
- RESIDUES;
- CEREBLON;
- COMPLEX;
52.Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N -linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity

机译：Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N -linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity
- 作者：Kour Parampreet;Saha Pallavi;Bhattacharya SrijaKumari DikshaDebnath AbhipsaRoy AmitSharma Deepak K.Mukherjee DebarajSingh Kuljit
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- ENHANCED CELLULAR UPTAKE;
- ALTERED PHARMACOKINETICS;
- TOXICITY;
- DONOVANI;
- 3,3'-DIINDOLYLMETHANES;
- DERIVATIVES;
- DISCOVERY;
- SYNTHASE;
53.Selective degradation-inducing probes for studying cereblon (CRBN) biology

机译：Selective degradation-inducing probes for studying cereblon (CRBN) biology
- 作者：Powell Chelsea E.;Du Guangyan;Bushman Jonathan W.He ZhixiangZhang TinghuFischer Eric S.Gray Nathanael S.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第8期
- DIFFERENTIAL EXPRESSION;
- LENALIDOMIDE;
- TARGET;
- IKAROS;
- GENE;
54.Discovery of benzoxazole-thiazolidinone hybrids as promising antibacterial agents against Staphylococcus aureus and Enterococcus species

机译：Discovery of benzoxazole-thiazolidinone hybrids as promising antibacterial agents against Staphylococcus aureus and Enterococcus species
- 作者：Cheerala Vijay Sai Krishna;Akhir Abdul;Saxena DeepanshiMaitra RahulChopra SidharthNeelakantan Sundaresan Chittor
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- ANTIBIOTICS;
- 4-THIAZOLIDINONES;
- BENZOTHIAZOLE;
- INHIBITORS;
- THERAPY;
- FAMILY;
55.The Mycobacterium tuberculosis mycothiol S-transferase is divalent metal-dependent for mycothiol binding and transfer

机译：The Mycobacterium tuberculosis mycothiol S-transferase is divalent metal-dependent for mycothiol binding and transfer
- 作者：Jayasinghe Yahani P.;Banco Michael T.;Lindenberger Jared J.Favrot LorenzaPalcekova ZuzanaJackson MaryManabe ShinoRonning Donald R.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第3期
- SMEGMATIS MUTANTS;
- THIOL;
- ERGOTHIONEINE;
- BIOSYNTHESIS;
- GENES;
- DINB;
56.SAR study of 4-arylazo-3,5-diamino-1H-pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms

机译：SAR study of 4-arylazo-3,5-diamino-1H-pyrazoles: identification of small molecules that induce dispersal of Pseudomonas aeruginosa biofilms
- 作者：Jansen Charlotte U.;Uhd Jesper;Andersen Jens B.Hultqvist Louise D.Jakobsen Tim H.Nilsson MartinNielsen Thomas E.Givskov MichaelTolker-Nielsen TimQvortrup Katrine M.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第11期
- INHIBITORS;
57.Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy

机译：Discovery of rigid biphenyl Plasmodium falciparum DHFR inhibitors using a fragment linking strategy
- 作者：Hoarau Marie;Sermmai Patpanat;Varatthan ThaveechaiThiabma RatthiyaJantra TararatRattanajak RoonglawanVitsupakorn DanooVanichtanankul JaruneeSaepua SiripornYuthavong YongyuthThongpanchang ChawaneeKamchonwongpaisan Sumalee
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- MALARIAL DIHYDROFOLATE-REDUCTASE;
- REFINEMENT;
- RESISTANCE;
58.Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052

机译：Structure-activity relationship studies on vitamin D-based selective SREBP/SCAP inhibitor KK-052
- 作者：Kawagoe Fumihiro;Mototani Sayuri;Mendoza AileenTakemoto YasushiUesugi MotonariKittaka Atsushi
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- LIPID-METABOLISM;
- DERIVATIVES;
- ACTIVATION;
- RECEPTOR;
59.Current leishmaniasis drug discovery

机译：Current leishmaniasis drug discovery
- 作者：Pinheiro Alessandra Campbell;Nora de Souza Marcus Vinicius
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第9期
- PRECLINICAL CANDIDATE;
- CUTANEOUS LEISHMANIASIS;
- INFECTIOUS-DISEASES;
- DIAGNOSIS;
- PATHOGENESIS;
- COMBINATION;
- EFFICACY;
- TARGETS;
- VACCINE;
- SERIES;
60.Recent advancements in chromone as a privileged scaffold towards the development of small molecules for neurodegenerative therapeutics

机译：Recent advancements in chromone as a privileged scaffold towards the development of small molecules for neurodegenerative therapeutics
- 作者：Madhav Hari;Jameel Ehtesham;Rehan MohammadHoda Nasimul
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第3期
- MONOAMINE-OXIDASE B;
- NEURAL STEM/PROGENITOR CELLS;
- ALZHEIMERS-DISEASE;
- HIPPOCAMPAL NEUROGENESIS;
- NEURONAL DIFFERENTIATION;
- INHIBITORS;
- HYBRIDS;
- POTENT;
- DERIVATIVES;
- DISCOVERY;
61.De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain

机译：De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain
- 作者：Thakkar Ravindra;Agarwal Dilip K.;Ranaweera Chathuranga B.Ishiguro SusumuConda-Sheridan MartinGaudreault Natasha N.Richt Juergen A.Tamura MasaakiComer Jeffrey
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- MOLECULAR-DYNAMICS SIMULATION;
- FREE-ENERGIES;
- INTERFACE;
- PREDICTION;
- DRUG;
- MUTATIONS;
- COMPLEXES;
62.Activity-based protein profiling reveals deubiquitinase and aldehyde dehydrogenase targets of a cyanopyrrolidine probe

机译：Activity-based protein profiling reveals deubiquitinase and aldehyde dehydrogenase targets of a cyanopyrrolidine probe
- 作者：Panyain Nattawadee;Godinat Aurelien;Thawani Aditya RaymondLachiondo-Ortega SofiaMason KatieElkhalifa SarahSmith Lisa M.Harrigan Jeanine A.Tate Edward W.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第11期
- UBIQUITIN;
- DISCOVERY;
- ENZYMES;
63.Druggable targets for the immunopathy of Alzheimer's disease

机译：Druggable targets for the immunopathy of Alzheimer's disease
- 作者：Weaver Donald F.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
64.Introduction to the themed collection on antimicrobial resistance

机译：Introduction to the themed collection on antimicrobial resistance
- 作者：Haldar Jayanta;Garneau-Tsodikova Sylvie;Fridman Micha
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
65.SF 5 - and SCF 3 -substituted tetrahydroquinoline compounds as potent bactericidal agents against multidrug-resistant persister Gram-positive bacteria

机译：SF 5 - and SCF 3 -substituted tetrahydroquinoline compounds as potent bactericidal agents against multidrug-resistant persister Gram-positive bacteria
- 作者：Onyedibe Kenneth I;Dayal Neetu;Sintim Herman O.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第11期
- STAPHYLOCOCCUS-AUREUS BACTEREMIA;
- INAPPROPRIATE USE;
- ANTIBIOTICS;
- INFECTIONS;
- MORTALITY;
66.Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers

机译：Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers
- 作者：Goddard Zoe Rachael;Beekman Andrew Michael;Cominetti Marco M. D.OConnell Maria A.Chambrier IsabelleCook Michael J.Marin Maria J.Russell David A.Searcey Mark
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第2期
- GROWTH-FACTOR RECEPTOR;
- CELLS;
- PHOTOSENSITIZERS;
- LIGAND;
- HEAD;
67.Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators

机译：Design, synthesis, and mechanistic study of 2-piperazineone-bearing peptidomimetics as novel HIV capsid modulators
- 作者：Zhang Xujie;Sun Lin;Xu ShujingHuang TianguangZhao FabaoDing DangLiu ChuanfengJiang XiangyiTao YucenKang DongweiDe Clercq ErikPannecouque ChristopheCocklin SimonDick AlexejLiu XinyongZhan Peng
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
- IMMUNODEFICIENCY-VIRUS TYPE-1;
- PHENYLALANINE DERIVATIVES;
- NITROAROMATIC COMPOUNDS;
- IDENTIFICATION;
- REPLICATION;
- DISCOVERY;
- GENOTOXICITY;
- INHIBITORS;
- INFECTION;
- TARGETS;
68.Pharmacological overview of hederagenin and its derivatives

机译：Pharmacological overview of hederagenin and its derivatives
- 作者：Huang Xing;Shen Qing-Kun;Guo Hong-YanLi XiaotingQuan Zhe-Shan
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- TANDEM MASS-SPECTROMETRY;
- PULSATILLA SAPONIN D;
- BIOLOGICAL EVALUATION;
- TRITERPENOID SAPONINS;
- HEMOLYTIC TOXICITY;
- DRUG-DELIVERY;
- RAT PLASMA;
- L. EXTRACT;
- IN-VITRO;
- ANTITUMOR;
69.Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators

机译：Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators
- 作者：Fernandez Kleinberg X.;Fischer Conrad;Vu JennieGheblawi MahmoudWang WangGottschalk SamanthaIturrioz XavierLlorens-Cortes CatherineOudit Gavin Y.Vederas John C.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第8期
- IDENTIFICATION;
- NEPRILYSIN;
- SYSTEM;
70.Design and synthesis of eugenol/isoeugenol glycoconjugates and other analogues as antifungal agents against Aspergillus fumigatus

机译：Design and synthesis of eugenol/isoeugenol glycoconjugates and other analogues as antifungal agents against Aspergillus fumigatus
- 作者：Goswami Lakshmi;Gupta Lovely;Paul SayantanVermani MaansiVijayaraghavan PoojaBhattacharya Asish K.
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第8期
- ANTIMICROBIAL ACTIVITY;
- CYCLOADDITION;
- SPECTRUM;
- EUGENOL;
- MELANIN;
- LUNG;
71.Dual functional therapeutics: mitigating bacterial infection and associated inflammation

机译：Dual functional therapeutics: mitigating bacterial infection and associated inflammation
- 作者：Acharya Yash;Taneja Kashish Kumar;Haldar Jayanta
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
72.Recent advancements in pharmacological strategies to modulate energy balance for combating obesity

机译：Recent advancements in pharmacological strategies to modulate energy balance for combating obesity
- 作者：Pati Benudhara;Sendh Satyabrata;Sahu BijayashreePani SunilJena NiveditaBal Naresh Chandra
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
73.Host-guest binding of tetracationic cyclophanes to photodynamic agents inhibits posttreatment phototoxicity and maintains antitumour efficacy

机译：Host-guest binding of tetracationic cyclophanes to photodynamic agents inhibits posttreatment phototoxicity and maintains antitumour efficacy
- 作者：Sun Jian-Da;Liu Yamin;Zhao ZijianYu Shang-BoQi Qiao-YanZhou WeiWang HuiHu KeZhang Dan-WeiLi Zhan-Ting
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第3期
- SYNTHETIC RECEPTOR;
- BOX;
- CYCLOBIS(PARAQUAT-PARA-PHENYLENE);
- PHOTOSENSITIZERS;
- CONSTRUCTION;
- CHEMISTRY;
- THERAPY;
- BLOCK;
- WATER;
74.Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity

机译：Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity
- 作者：De Luca Laura;Lombardo Lisa;Mirabile SalvatoreMarrazzo AgostinoDichiara MariaCosentino GiuseppeAmata EmanueleGitto Rosaria
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
75.Biphenyl scaffold for the design of NMDA-receptor negative modulators: molecular modeling, synthesis, and biological activity

机译：Biphenyl scaffold for the design of NMDA-receptor negative modulators: molecular modeling, synthesis, and biological activity
- 作者：Karlov Dmitry S.;Temnyakova Nadezhda S.;Vasilenko Dmitry A.Barygin Oleg IDron Mikhail Y.Zhigulin Arseniy S.Averina Elena B.Grishin Yuri K.Grigoriev Vladimir V.Gabrelyan Alexey VAniol Viktor A.Gulyaeva Natalia VOsipenko Sergey VKostyukevich Yury IPalyulin Vladimir A.Popov Petr A.Fedorov Maxim V
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第7期
- IFENPRODIL;
- PREDICTION;
- MECHANISM;
- INHIBITION;
- ACTIVATION;
- BLOCKADE;
- KETAMINE;
- BINDING;
76.Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction

机译：Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEAD·YAP1 interaction
- 作者：Bum-Erdene Khuchtumur;Ghozayel Mona K.;Zhang Mark J.Gonzalez-Gutierrez GiovanniMeroueh Samy O.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
77.Design, synthesis and in vitro cytotoxicity evaluation of indolo-pyrazoles grafted with thiazolidinone as tubulin polymerization inhibitors

机译：Design, synthesis and in vitro cytotoxicity evaluation of indolo-pyrazoles grafted with thiazolidinone as tubulin polymerization inhibitors
- 作者：Soni Jay Prakash;Chilvery Shrilekha;Sharma AnamikaReddy G. NikithaGodugu ChandraiahShankaraiah Nagula
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第3期
- MICROTUBULE INHIBITOR;
- BIOLOGICAL EVALUATION;
- ANTICANCER ACTIVITY;
- CANCER;
- DERIVATIVES;
- GLYOXYLAMIDES;
- INDIBULIN;
- SCAFFOLD;
- ANALOGS;
- D-24851;
78.Synthesis of tryptanthrin appended dispiropyrrolidine oxindoles and their antibacterial evaluation

机译：Synthesis of tryptanthrin appended dispiropyrrolidine oxindoles and their antibacterial evaluation
- 作者：Leena Sruthi Sudheendran;Akhir Abdul;Saxena DeepanshiMaitra RahulChopra SidharthDeepthi Ani
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- 1,3-DIPOLAR CYCLOADDITION;
79.Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood-brain barrier permeability

机译：Second-generation tricyclic pyrimido-pyrrolo-oxazine mTOR inhibitor with predicted blood-brain barrier permeability
- 作者：Borsari Chiara;Keles Erhan;Treyer AndreaDe Pascale MartinaHebeisen PaulHamburger MatthiasWymann Matthias P.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第4期
- POTENT;
- SULFAMIDATE;
- DISCOVERY;
- PENETRANT;
- PI3K;
80.Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides

机译：Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides
- 作者：Pomplun Sebastian
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第2期
- POTENT;
- SPIKE;
- ACE2;
- DESIGN;
- ENTRY;
81.Anti-proliferative activity of nitroquinolone fused acylhydrazones as non-small cell human lung cancer agents

机译：Anti-proliferative activity of nitroquinolone fused acylhydrazones as non-small cell human lung cancer agents
- 作者：Nandakumar Vandana;Sundarasamy Amsaveni;Adhigaman KaviyarasuRamasamy Sentamil SelviPaulpandi ManickamKodiveri Muthukaliannan GothandamNarayanasamy ArulThangaraj Suresh
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
82.Medicinal chemistry approaches to target the MNK-eIF4E axis in cancer

机译：Medicinal chemistry approaches to target the MNK-eIF4E axis in cancer
- 作者：Fernandez Ann;Monsen Paige J.;Platanias Leonidas C.Schiltz Gary E.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
83.Dual FLT3/haspin kinase inhibitor based on 3 H -pyrazolo4,3- f quinoline scaffold with activities against acute myeloid leukemia

机译：Dual FLT3/haspin kinase inhibitor based on 3 H -pyrazolo4,3- f quinoline scaffold with activities against acute myeloid leukemia
- 作者：Kempen Allison L.;Brauer Nickolas R.;Sintim Herman O.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- FLT3;
84.Hypoxia-activated prodrugs of phenolic olaparib analogues for tumour-selective chemosensitisation

机译：Hypoxia-activated prodrugs of phenolic olaparib analogues for tumour-selective chemosensitisation
- 作者：Wong Way W.;OBrien-Gortner Sophia F.;Anderson Robert F.Wilson William R.Hay Michael P.Dickson Benjamin D.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
- POLY(ADP-RIBOSE) POLYMERASE PARP;
- CARBAMATE PRODRUGS;
- POTENT INHIBITORS;
- DESIGN;
- OXIDOREDUCTASE;
- COMBINATION;
- REDUCTION;
- EFFICACY;
- THERAPY;
- REPAIR;
85.Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors

机译：Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors
- 作者：Gulati Anmol;Yeung Charles S.;Lapointe BlairKattar Solomon D.Gunaydin HakanScott Jack D.Childers Kaleen K.Methot Joey L.Simov VladimirKurukulasuriya RaviPio BarbaraMorriello Greg J.Liu PingTang HaiqunNeelamkavil SanthoshWood Harold B.Rada Vanessa L.Ardolino Michael J.Yan Xin CindyPalte RachelOtte KarinFaltus RobertWoodhouse JaniceHegde Laxminarayan G.Ciaccio PaulMinnihan Ellen C.DiMauro Erin F.Fell Matthew J.Fuller Peter H.Ellis J. Michael
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第7期
- PARKINSONS-DISEASE;
- MOTOR FLUCTUATIONS;
- DISCOVERY;
- MUTATIONS;
- DESIGN;
- POTENT;
86.Discovery of FtsZ inhibitors by virtual screening as antibacterial agents and study of the inhibition mechanism

机译：Discovery of FtsZ inhibitors by virtual screening as antibacterial agents and study of the inhibition mechanism
- 作者：Du Ruo-Lan;Sun Ning;Fung Yik-HongZheng Yuan-YuanChen Yu-WeiChan Pak-HoWong Wing-LeungWong Kwok-Yin
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第1期
- DIVISION PROTEIN FTSZ;
- CELL-DIVISION;
- STAPHYLOCOCCUS-AUREUS;
- ASSEMBLY DYNAMICS;
- SMALL-MOLECULE;
- IDENTIFICATION;
- VANCOMYCIN;
- INSIGHTS;
- TARGETS;
87.Recent developments of imidazo1,2-apyridine analogues as antituberculosis agents

机译：Recent developments of imidazo1,2-apyridine analogues as antituberculosis agents
- 作者：Samanta Sauvik;Kumar Sumit;Aratikatla Eswar K. K.Ghorpade Sandeep R. R.Singh Vinayak
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第4期
- MYCOBACTERIUM-TUBERCULOSIS;
- BIOLOGICAL EVALUATION;
- CLINICAL CANDIDATE;
- CHEMICAL ENTITIES;
- DRUG DISCOVERY;
- INHIBITORS;
- Q203;
- IDENTIFICATION;
- BENZOTHIAZINONES;
- DERIVATIVES;
88.Discovery of 2,3-dihydro-1 H -pyrrolo3,4- b quinolin-1-one derivatives as possible antileishmanial agents

机译：Discovery of 2,3-dihydro-1 H -pyrrolo3,4- b quinolin-1-one derivatives as possible antileishmanial agents
- 作者：Seth Anuradha;Ghoshal Anirban;Dewaker VarunRani AnkitaSingh Sangh PriyaDutta MukulKatiyar ShivaniSingh Sandeep KumarRashid MamunurWahajuddin MuhammadKar SusantaSrivastava Ajay Kumar
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第6期
- TOPOISOMERASE-I INHIBITORS;
- DNA TOPOISOMERASES;
- LEISHMANIA-DONOVANI;
- BETA-LACTAMS;
- CAMPTOTHECIN;
- CONSTRUCTION;
- SITAMAQUINE;
- MECHANISM;
- LIBRARIES;
89.Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn(ii), Co(ii) and Ni(ii) complexes – combined experimental and theoretical measurements towards DNA/BSA/SARS-CoV-2 3CLPro

机译：Exploring the antioxidant, antimicrobial, cytotoxic and biothermodynamic properties of novel morpholine derivative bioactive Mn(ii), Co(ii) and Ni(ii) complexes – combined experimental and theoretical measurements towards DNA/BSA/SARS-CoV-2 3CLPro
- 作者：Sakthikumar Karunganathan;Kabuyaya Isamura Bienfait;Krause Rui Werner Maçedo
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
90.Design, synthesis, and anti-hepatocellular carcinoma of thiopyrimidine/chalcone hybrids as dual STAT3/STAT5 inhibitors

机译：Design, synthesis, and anti-hepatocellular carcinoma of thiopyrimidine/chalcone hybrids as dual STAT3/STAT5 inhibitors
- 作者：Altwaijry Najla;Sabour Rehab;Ibrahim Mona H. H.Al Kamaly OmkulthomAbdullah OmeimaHarras Marwa F. F.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- BIOLOGICAL EVALUATION;
- SIGNAL TRANSDUCER;
- CHALCONE DERIVATIVES;
- MOLECULAR TARGETS;
- STAT3;
- ACTIVATOR;
- POTENT;
- APOPTOSIS;
- BINDING;
- CANCER;
91.Contents list

机译：Contents list
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第7期
92.Microwave-assisted green synthesis of bile acid derivatives and evaluation of glucocorticoid receptor binding

机译：Microwave-assisted green synthesis of bile acid derivatives and evaluation of glucocorticoid receptor binding
- 作者：Vasiljevic Bojana R.;Petri Edward T.;Beki Sofija S.Celic Andjelka S.Grbovic Ljubica M.Pavlovic Ksenija J.
- 期刊名称：《RSC Medicinal Chemistry》 | 2021年第2期
- OXIDATION;
- REDUCTIONS;
- AMIDES;
93.Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEADYAP1 interaction

机译：Chloroacetamide fragment library screening identifies new scaffolds for covalent inhibition of the TEADYAP1 interaction
- 作者：Bum-Erdene Khuchtumur;Ghozayel Mona K.;Zhang Mark J.Gonzalez-Gutierrez GiovanniMeroueh Samy O.
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期
- HIPPO PATHWAY;
- YAP;
- TEAD;
- GROWTH;
- INDUCTION;
- COMPONENT;
- YORKIE;
- LATS;
94.N -Acylsulfonamide: a valuable moiety to design new sulfa drug analogues

机译：N -Acylsulfonamide: a valuable moiety to design new sulfa drug analogues
- 作者：Amador Romain;Tahrioui Ali;Barreau MagalieLesouhaitier OlivierSmietana MichaelClave Guillaume
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第8期
- ACYL SULFONAMIDES;
- EFFICIENT METHOD;
- ACID;
- RESISTANCE;
- MECHANISM;
- ACYLATION;
- INHIBITORS;
- DISCOVERY;
- SECONDARY;
- SCAFFOLD;
95.Fragment screening at AstraZeneca: developing the next generation biophysics fragment set

机译：Fragment screening at AstraZeneca: developing the next generation biophysics fragment set
- 作者：Lucas Simon C. C.;Borjesson Ulf;Bostock Mark J.Cuff JohnEdfeldt FredrikEmbrey Kevin J.Eriksson Per-OlofGohlke AndreaGunnarson AndersLainchbury MichaelMilbradt Alexander G.Moore RachelRawlins Philip B.Sinclair IanStubbs ChristopherStorer R. Ian
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第9期
- LEAD GENERATION;
- LIBRARIES;
- DESIGN;
96.Morpholine substituted quinazoline derivatives as anticancer agents against MCF-7, A549 and SHSY-5Y cancer cell lines and mechanistic studies

机译：Morpholine substituted quinazoline derivatives as anticancer agents against MCF-7, A549 and SHSY-5Y cancer cell lines and mechanistic studies
- 作者：Dwivedi Ashish Ranjan;Kumar Vijay;Prashar VikashVerma AkashKumar NaveenParkash JyotiKumar Vinod
- 期刊名称：《RSC Medicinal Chemistry》 | 2022年第5期
- TETRAHYDROCURCUMIN DERIVATIVES;
- ANTITUMOR-ACTIVITY;
- BCL-2 INHIBITOR;
- APOPTOSIS;
- CASPASE-3;
- APPROVAL;
97.Detection of intact vancomycin-arginine as the active antibacterial conjugate in E. coli by whole-cell solid-state NMR

机译：Detection of intact vancomycin-arginine as the active antibacterial conjugate in E. coli by whole-cell solid-state NMR
- 作者：Werby Sabrina H.;Brcic Jasna;Chosy Madeline B.Sun JiuzhiRendell Jacob T.Neville Lewis F.Wender Paul A.Cegelski Lynette
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
98.Exploration of tricyclic heterocycles as core structures for RIOK2 inhibitors

机译：Exploration of tricyclic heterocycles as core structures for RIOK2 inhibitors
- 作者：Xiong Huilan;Yu Qiuchun;Ma HaowenYu XiuwenOuyang YifanZhang Zhi-MinZhou WeiZhang ZhangCai Qian
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第10期
- PROTEIN-KINASE;
- FAMILY;
- BIOGENESIS;
99.Analytical insights into the detoxification process and characterization of a traditional metallopharmaceutical formulation

机译：Analytical insights into the detoxification process and characterization of a traditional metallopharmaceutical formulation
- 作者：Malarvizhi K.;Vedha Hari B. N.;Rajalakshmi P.Devaraj S.Durai Ramyadevi
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第6期
- SPECTROSCOPIC CHARACTERIZATION;
- SULFUR NANOPARTICLES;
- ARSENIC TRIOXIDE;
- ANTICANCER;
- SULFIDE;
- MERCURY;
- DRUGS;
- INHIBITION;
- KINETICS;
- AGENTS;
100.De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain

机译：De novo design of a stapled peptide targeting SARS-CoV-2 spike protein receptor-binding domain
- 作者：Thakkar Ravindra;Agarwal Dilip K.;Ranaweera Chathuranga B.Ishiguro SusumuConda-Sheridan MartinGaudreault Natasha N.Richt Juergen A.Tamura MasaakiComer Jeffrey
- 期刊名称：《RSC Medicinal Chemistry》 | 2023年第9期

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