• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>BMC Infectious Diseases >Eighteen-year follow-up report of the surveillance and prevention of an HIV/AIDS outbreak amongst plasma donors in Hebei Province, China
【24h】

Eighteen-year follow-up report of the surveillance and prevention of an HIV/AIDS outbreak amongst plasma donors in Hebei Province, China

机译：中国河北省血浆捐赠者中艾滋病毒/艾滋病暴发监测与预防的十八年随访报告

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

There has been a clear increase in HIV-1 infection cases in recent years in Hebei Province, China, and transmission via blood is one of the risk factors in the early. This article aimed to investigate the HIV infection rate and control efficiency among the paid blood donor population over a period of 18?years. From 1995–2013, HIV/AIDS cases among former blood donors in Hebei Province were registered and closely monitored to collect data of all-cause mortality, intervention measures to prevent family transmission, disease transmission between couples as well as between mothers and infants, and HAART therapy outcomes. A total of 326 cases were identified as directly infected with HIV/AIDS during plasma donation in Hebei Province. Of these, 146 cases (44.8?%) were identified in the same year as infection; 180 cases (55.2?%) were identified 1–18?years after infection because they did not participate in the 1995 screening. The final case was identified in February 2012. By 2013, the mortality rate and survival rate of plasma donor-related HIV/AIDS was 54.9 % and 45.1?%, respectively. The identified transmission rate between couples was 11.3?% (8/71); this rate during the same year as infection was 3.3?% (1/30), and the rate 4–17?years after HIV infection was 17.1?% (7/41). Approximately 91.2?% (145/159) of married women of childbearing age did not have children after being informed of HIV infection. Only 8.8?% (14/159) of these women had children after being informed of HIV infection. The mother-to-infant transmission rate was 38.5?% (5/13). The HAART coverage rate has increased from 10.1?% (16/159) in 2003 to 83.6?% (127/152) in 2013. Since 1999, the HIV mortality rate has trended up; by 2013, the cumulative mortality rate reached 54.9?% (179/326). After HAART was initiated in China, the death rate decreased to some extent. Second generation transmission (via couple or mother-to-infant transmission) among blood donor-related HIV cases accounted for approximately 4.0?% (13/326). All first- or second-generation cases were infected with HIV-1 subtype B. In this accident of HIV-infection among plasma donors in Hebei Province, a total of 339 direct and second-generation cases have been identified over 18?years of monitoring. Favorable clinical results have been achieved using intervention measurements and antiviral therapy.
机译：近年来，中国河北省的HIV-1感染病例明显增加，而通过血液传播是早期的危险因素之一。本文旨在调查有偿献血者在18年内的HIV感染率和控制效率。从1995年至2013年，对河北省原献血者中的HIV / AIDS病例进行了登记并受到密切监测，以收集全因死亡率数据，预防家庭传播的干预措施，夫妻之间以及母婴之间的疾病传播，以及HAART治疗结果。在河北省，共鉴定出326例血浆捐赠过程中直接感染HIV / AIDS的病例。在同一年中，有146例病例（占44.8％）被确定为感染。由于他们没有参加1995年的筛查，因此在感染后1-18年内发现了180例病例（55.2％）。最终病例于2012年2月确定。到2013年，血浆供体相关HIV / AIDS的死亡率和存活率分别为54.9％和45.1％。夫妻之间的确定传输率为11.3％（8/71）;在感染的同一年，该比率为3.3％（1/30），而在HIV感染后4-17年的这一比率为17.1％（7/41）。大约91.2％（145/159）的育龄已婚妇女在被告知艾滋病毒感染后没有孩子。这些妇女中只有8.8％（14/159）的妇女在得知艾滋病毒感染后才育有孩子。母婴传播率为38.5％（5/13）。 HAART覆盖率已从2003年的10.1％（16/159）增加到2013年的83.6％（127/152）。自1999年以来，艾滋病毒死亡率呈上升趋势。到2013年，累计死亡率达到54.9％（179/326）。在中国启动HAART后，死亡率有所下降。在与献血者有关的艾滋病毒病例中，第二代传播（通过夫妇或母婴传播）约占4.0％（13/326）。第一代或第二代所有病例都感染了B型HIV-1亚型。在这次河北省血浆供者间的HIV感染事故中，经过18年的监测，总共确定了339例直接和第二代病例。 。使用干预措施和抗病毒治疗已取得了良好的临床效果。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号