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Screening for celiac disease in average-risk and high-risk populations

机译:在高危人群和高危人群中筛查乳糜泻

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The prevalence of celiac disease is rising. As a result there is increasing interest in the associated mortality and morbidity of the disease. Screening of asymptomatic individuals in the general population is not currently recommended; instead, a strategy of case finding is the preferred approach, taking into account the myriad modes of presentation of celiac disease. Although a gluten-free diet is the treatment of choice in symptomatic patients with celiac disease, there is no consensus on whether institution of a gluten-free diet will improve the quality of life in asymptomatic screen-detected celiac disease patients. A review of the studies that have been performed on this subject is presented. Certain patient groups such as those with autoimmune diseases may be offered screening in the context of an informed discussion regarding the potential benefits, with the caveat that the data on this issue are sparse. Active case finding seems to be the most prudent option in most clinical situations.
机译:腹腔疾病的患病率正在上升。结果,人们对该疾病的相关死亡率和发病率越来越感兴趣。目前不建议对一般人群中无症状的个体进行筛查;取而代之的是,考虑到腹腔疾病的多种表现方式,病例发现策略是首选方法。尽管无麸质饮食是有症状的腹腔疾病患者的首选治疗方法,但对于无症状饮食筛查的腹腔疾病患者,无麸质饮食的使用是否会改善生活质量尚无共识。提出了对此主题的研究综述。某些患者群体(例如自身免疫性疾病患者)可能会在有关潜在益处的知情讨论的背景下进行筛查,但需要注意的是,有关此问题的数据很少。在大多数临床情况下,主动寻找病例似乎是最谨慎的选择。

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