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首页> 外文期刊>Physiology & behavior >Sex differences in energy homeostatis following a diet relatively high in protein exchanged with carbohydrate, assessed in a respiration chamber in humans.
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Sex differences in energy homeostatis following a diet relatively high in protein exchanged with carbohydrate, assessed in a respiration chamber in humans.

机译：在人的呼吸腔中评估，与碳水化合物交换的蛋白质相对较高的饮食后，能量稳态的性别差异。

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CONTEXT: Obesity prevalence is generally higher in women than in men, and a paucity of research with sex-specific approaches exists. The question arises whether current weight loss programmes, largely developed and tested on women, are appropriate for men. OBJECTIVE: Investigate 24 h energy metabolism, satiety and related hormones during a diet relatively high in protein (HP), exchanged with carbohydrate compared to an adequate-protein (AP) diet, in a respiration chamber in men, in comparison with previous outcomes in women. DESIGN: Ten healthy males (BMI: 22.5+/-1.6 kg/m(2), age: 25+/-3.5 y) were fed in energy balance with an AP (10/60/30% of energy of protein/carbohydrate/fat) or a HP (30/40/30% of energy of protein/carbohydrate/fat) diet in a randomized cross-over design. RESULTS: During the HP diet, 24 h Energy Expenditure (10.5+/-0.5 vs 10.0+/-0.5 MJ/d; p<0.05), Sleeping Energy Expenditure (7.1+/-0.3 vs 6.9+/-0.2 MJ/d; p<0.05), protein balance (0.5+/-0.02 vs 0.0+/-0.01 MJ/d; p<0.05), satiety (AUC) p<0.05, and plasma GLP-1 concentrations (42+/-23 vs 28+/-16 AUC; p<0.005) were significantly higher and 24 h RQ (0.80 vs 0.85; p<0.01), fat balance (-0.85+/-0.03 vs 0.05 vs 0.03 MJ/d; p<0.01) and hunger (AUC) p<0.05, were significantly lower. Comparisons reveal a stronger reaction in men in energy expenditure and substrate oxidation, whereas satiety reacted stronger in the women. CONCLUSIONS: Effects of a diet relatively high in protein exchanged with carbohydrate, vs an adequate protein diet are a stronger increased energy expenditure, fat oxidation, protein anabolism in men, and a stronger increased satiety in women, thereby creating sex-specific conditions for long-term use for body-weight management.
机译：背景：肥胖症的患病率通常比男性高，而且针对性别的研究很少。问题是，目前的减肥计划（主要针对妇女制定和测试）是否适合男性。目的：与男性先前的结果相比，在男性的呼吸室内调查相对高蛋白（AP）饮食与碳水化合物相比，蛋白质（HP）相对较高的饮食中24小时能量代谢，饱腹感和相关激素。女人。设计：十只健康的男性（BMI：22.5 +/- 1.6 kg / m（2），年龄：25 +/- 3.5岁）以能量平衡的AP（蛋白质/碳水化合物能量的10/60/30％）进食/脂肪）或采用随机交叉设计的HP（蛋白质/碳水化合物/脂肪能量的30/40/30％）饮食。结果：在HP饮食期间，24小时能量消耗（10.5 +/- 0.5 vs 10.0 +/- 0.5 MJ / d; p <0.05），睡眠能量消耗（7.1 +/- 0.3 vs 6.9 +/- 0.2 MJ / d ; p <0.05），蛋白质平衡（0.5 +/- 0.02与0.0 +/- 0.01 MJ / d; p <0.05），饱腹感（AUC）p <0.05和血浆GLP-1浓度（42 +/- 23 vs 28 +/- 16 AUC; p <0.005）和24小时RQ（0.80 vs 0.85; p <0.01），脂肪平衡（-0.85 +/- 0.03 vs 0.05 vs 0.03 MJ / d; p <0.01）和24 h RQ显着更高饥饿（AUC）p <0.05，显着降低。比较表明，男性在能量消耗和底物氧化方面反应较强，而饱腹感在女性体内反应较强。结论：与碳水化合物交换的蛋白质相对较高的饮食与适当的蛋白质饮食相比，男性的能量消耗增加，脂肪氧化，蛋白质合成代谢增强，女性的饱腹感增强，从而长期造成针对性别的状况长期用于体重管理。

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