Iconix Pharmaceuticals, Inc.--removing barriers to efficient drug discovery through chemogenomics.

Engelberg A

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Iconix Pharmaceuticals, Inc.--removing barriers to efficient drug discovery through chemogenomics.

机译：Iconix Pharmaceuticals，Inc.-通过化学基因组学消除了有效药物发现的障碍。

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Iconix Pharmaceuticals, Inc. is pioneering the new field of chemogenomics--the integration of chemistry and genomics to profile, optimize and monitor clinical candidates and drug treatment. Iconix's chemogenomic capabilities enable pharmaceutical companies to increase the odds of advancing the right compounds to the clinic and managing the development of those compounds in human testing, thus reducing attrition rates and the costs of drug discovery.

机译：Iconix Pharmaceuticals，Inc.开拓了化学基因组学的新领域-化学和基因组学的集成，以分析，优化和监控临床候选药物和药物治疗。 Iconix的化学基因组学能力使制药公司能够提高将正确的化合物推向临床并管理这些化合物在人体测试中的发展的可能性，从而降低人员流失率和药物开发成本。

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《Pharmacogenomics》 |2004年第6期|共4页
作者
Engelberg A;
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正文语种 eng
中图分类药学;
关键词
drug discovery; membership attrition; Clinic; development aspects;

机译：药物发现;成员流失;临床;发展方面;

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1. Iconix Pharmaceuticals, Inc.--removing barriers to efficient drug discovery through chemogenomics. [J] . Engelberg A Pharmacogenomics . 2004,第6期

机译：Iconix Pharmaceuticals，Inc.-通过化学基因组学消除了有效药物发现的障碍。
2. The use of in vitro cell culture models for mechanistic studies and as permeability screens for the blood-brain barrier in the pharmaceutical industry--background and current status in the drug discovery process. [J] . Lundquist S, Renftel M Vascular pharmacology . 2002,第6期

机译：使用体外细胞培养模型进行机理研究以及用作制药行业血脑屏障的通透性筛选-药物发现过程的背景和当前状态。
3. PHARMACEUTICAL & DRUG DISCOVERY: "Lab-on-Chip" Drug Discovery & Development - Microfluidic Devices and Artificial Cells [J] . Dario Lombardi, Petra S. Dittrich G.I.T. Laboratory Journal Europe . 2010,第3a4期

机译：药物与药品的发现：“芯片实验室”药物的发现与开发-微流控设备和人工细胞
4. MALDI Imaging of Pharmaceuticals in Zebrafish for Discovery and Drug Safety Screening [C] . Stacey R. Oppenheimer, Jiangwei Li, John B. Sciarra American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：斑马鱼中药品的Maldi成像，用于发现和药物安全筛查
5. Drug discovery from marine microbes A chemical evaluation of Hawaiian marine microbial biodiversity and its potential towards the discovery of novel antibiotic and anticancer pharmaceuticals. [D] . Feher, Domonkos. 2010

机译：从海洋微生物中发现药物夏威夷海洋微生物生物多样性的化学评估及其在发现新型抗生素和抗癌药物方面的潜力。
6. Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood–Retinal Barrier Model for Use in Early Drug Discovery [O] . Laura Hellinen, Heidi Hongisto, Eva Ramsay, 2020

机译：跨RPE细胞模型的药物通量：寻求在早期药物发现中使用的适当的外血-视网膜屏障模型
7. A Novel and Efficient Continuous-Flow Route To Prepare Trifluoromethylated N-Fused Heterocycles for Drug Discovery and Pharmaceutical Manufacturing [O] . Lara Amini-Rentsch, Ennio Vanoli, Sylvia Richard-Bildstein, 2019

机译：一种新颖且有效的连续流动途径，用于制备三氟甲基化的N-融合杂环用于药物发现和药物制造

Iconix Pharmaceuticals, Inc.--removing barriers to efficient drug discovery through chemogenomics.

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