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Magnesium in health and disease.

机译：镁在健康和疾病中。

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Introduction: Magnesium is an essential electrolyte in living organisms, which has to be supplied daily in a sufficient amount. Methods: The clinical importance of a magnesium overload or a magnesium intoxication is seldom. However, a magnesium deficiency is of special importance in humans, despite of a normal magnesium supplementation. The primary effect of a magnesium deficiency results in a reduction of energy production. This reduced energy production can result in a disturbed membrane function, calcium magnesium antagonism and cell dysfunction. Results: Thereby consequences may result in an organ dysfunction and an altered answer to external and internal stress. The reduced energy status is responsible for the recovery of unhealthy individuals - e.g. cardiac arrhythmias, primary hypertension, pre-eclampsia, cramps, allergic reactions - upon repletion of Mg status. Conclusions: The importance of an oral or intravenously supplementation of magnesium has often been described in a variety of diseases. In addition of special interest is the use of magnesium in critically ill patients in intensive care medicine.
机译：简介：镁是生物体中必不可少的电解质，每天必须提供足够量的镁。方法：镁超载或镁中毒的临床重要性很少。然而，尽管补充了正常的镁，但镁缺乏对人类来说却尤为重要。镁缺乏的主要作用导致能量产生的减少。这种减少的能量产生可导致膜功能受损，钙镁拮抗作用和细胞功能障碍。结果：因此，后果可能导致器官功能障碍以及对内外压力的改变。减少的能量状态是导致不健康个体恢复的原因-例如心律失常，原发性高血压，先兆子痫，痉挛，过敏反应-补充镁状态。结论：口服或静脉内补充镁的重要性在多种疾病中经常被描述。另外，在重症监护医学中对重症患者使用镁还有特别的意义。

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