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首页> 外文期刊>Plant Foods for Human Nutrition >Effect of coconut palm wine (Toddy) on carbohydrate metabolism in pregnant rats and fetuses.
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Effect of coconut palm wine (Toddy) on carbohydrate metabolism in pregnant rats and fetuses.

机译：可可椰子酒（托迪）对孕妇和胎儿碳水化合物代谢的影响。

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The objective of this study was to determine the effects of an alcoholic beverage (Toddy) and the equivalent quantity of ethanol on carbohydrate metabolism in utero. Female albino Sprague-Dawley rats were exposed to Toddy from coconut palm (24.5) and ethanol (0.52 ml/kg body weight daily) for 15 days before conception and throughout gestation. On the 19th day of gestation, hypoglycaemia was seen in both the treated groups, but it was more in the Toddy-treated group. Synthesis of glycogen was elevated on exposure to ethanol/Toddy but its degradation was enhanced only in alcohol-exposed rats. Key enzymes of the citric acid cycle and gluconeogenesis were inhibited on administration of alcohol and Toddy. Activity of glycolytic enzymes were increased.Toddy seemed to potentiate the toxicity induced by alcohol, indicating the additive effects of congeners.
机译：这项研究的目的是确定酒精饮料（Toddy）和当量乙醇对子宫内碳水化合物代谢的影响。雌性白化病Sprague-Dawley大鼠在受孕前和整个妊娠过程中，要接受椰子汁（24.5）和乙醇（每天0.52 ml / kg体重）的Toddy暴露15天。妊娠第19天，两个治疗组均出现低血糖症，但在Toddy治疗组中偏高。暴露于乙醇/托迪时，糖原的合成增加，但仅在酒精暴露的大鼠中，糖原的降解增加。柠檬酸循环和糖异生的关键酶被抑制酒精和托迪的管理。糖酵解酶的活性增加。托迪似乎增强了酒精诱导的毒性，表明同类物的累加作用。

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