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首页> 外文期刊>Plant Foods for Human Nutrition >Effect of inclusion of cashew globulin (Anacardium occidentale) to acasein diet on lipid parameters in rats
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Effect of inclusion of cashew globulin (Anacardium occidentale) to acasein diet on lipid parameters in rats

机译：酪蛋白饮食中加入腰果球蛋白（Anacardium occidentale）对大鼠脂质参数的影响

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The effect of inclusion of cashew globulin to a casein diet on lipid metabolism was studied in rats fed diets with two levels of cashew globulin meal. Inclusion of cashew globulin to a casein diet produced lower levels of total cholesterol, triacylglycerol and phospholipids in the serum and tissues and lower levels of serum lipoprotein cholesterol. There was decreased cholesterogenesis in the liver as evidenced by decreased activity of HMG CoA reductase and decreased release of lipoproteins into circulation. Rats fed cashew globulin along with casein also showed higher activity of LPL in the heart and adipose tissue and higher activity of LCAT. Increased hepatic diversion of cholesterol to bile acid synthesis and increased excretion of bile acids and sterols were also observed in these groups. Activity of glucose-6-phosphate dehydrogenase and malic enzyme was decreased in rats fed cashew globulin along with casein. This study demonstrates that cashew globulins included in the diet of rats are able to alter lipid metabolism which results in lower levels of lipid parameters in the serum and tissues.
机译：在以两种水平的腰果粉饮食喂养的大鼠中研究了酪蛋白饮食中包含腰果球蛋白对脂质代谢的影响。酪蛋白饮食中包含腰果球蛋白会降低血清和组织中的总胆固醇，三酰甘油和磷脂水平，并降低血清脂蛋白胆固醇水平。 HMG CoA还原酶活性降低和脂蛋白向循环系统的释放降低证明了肝脏中胆固醇生成的降低。腰果球蛋白和酪蛋白一起喂养的大鼠在心脏和脂肪组织中还表现出更高的LPL活性，同时也表现出更高的LCAT活性。在这些组中，还观察到胆固醇从肝转移到胆汁酸合成的增加以及胆汁酸和固醇的排泄增加。在腰果球蛋白和酪蛋白一起喂养的大鼠中，葡萄糖-6-磷酸脱氢酶和苹果酸酶的活性降低。这项研究表明，大鼠饮食中所含的腰果球蛋白能够改变脂质代谢，从而降低血清和组织中脂质参数的水平。

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