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首页> 外文期刊>Chemical Senses >Alarm Pheromone that Aggravates Stress-induced Hyperthermia is Soluble in Water
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Alarm Pheromone that Aggravates Stress-induced Hyperthermia is Soluble in Water

机译：加剧应激诱导的体温过高的警报信息素在水中可溶

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We previously reported that stressed male Wistar rats released alarm pheromone from the perianal region,which aggravated stress-induced hyperthermia and increased Fos expression in the mitral/tufted cell layer of the accessory olfactory bulb in recipient rats.In this study,we attempted to obtain this pheromone in water using these responses as bioassay parameters.Water droplets were collected from the ceiling of a box in which no animal was placed,or from a box in which an anesthetized donor rat was given electrical stimulation to either the neck or perianal regions in order to induce neck odor or alarm pheromone release,respectively.Then we placed one of the three kinds of water-containing filter papers on the wall of a recipient's home cage and observed heart rate,body temperature and behavioral responses,as well as Fos expression in the main and accessory olfactory bulbs of the recipient.The water collected from the box containing the alarm pheromone was found to generate a reproduction of all of the responses seen in the animal that had been directly exposed to alarm pheromone in our previous studies.These results suggest that the alarm pheromone is soluble in water.
机译：我们以前曾报道过，压力过大的雄性Wistar大鼠从肛周区域释放出警报信息素，从而加剧了压力诱发的体温过高，并增加了受体大鼠副嗅球的二尖瓣/簇状细胞层中Fos的表达。在本研究中，我们试图获得使用这些响应作为生物测定参数，将水中的信息素从未放置任何动物的盒子的天花板上或从麻醉的供体大鼠受到电刺激的颈部或肛周区域的盒子中收集水滴。然后分别将三种含水滤纸中的一种放在受者笼子的墙壁上，观察心率，体温和行为反应以及Fos的表达。从接收者的主嗅球和副嗅球中发现，从装有警报信息素的盒子中收集的水产生了复制品在我们先前的研究中，直接观察到警报信息素的动物中发现的所有反应均得到证实，这些结果表明警报信息素可溶于水。

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