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首页> 外文期刊>Physiotherapy theory and practice >Positive pressure - analysing the effect of the addition of non-invasive ventilation (NIV) to home airway clearance techniques (ACT) in adult cystic fibrosis (CF) patients
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Positive pressure - analysing the effect of the addition of non-invasive ventilation (NIV) to home airway clearance techniques (ACT) in adult cystic fibrosis (CF) patients

机译：正压-分析在成人囊性纤维化（CF）患者中向家庭气道清除技术（ACT）添加无创通气（NIV）的效果

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摘要

Background: There is no published literature on the frequency of use of non-invasive ventilation (NIV) with airway clearance techniques (ACT) throughout the cystic fibrosis (CF) population; 3.9% (191 people of 5062 registered) of the United Kingdom CF population older than 16 years are reported to use NIV in registry data; however, it is not specified if this is for ACT or respiratory failure. Using NIV with ACT decreases work of breathing and fatigue during inpatient admissions for CF patients. We hypothesised these effects could be replicated at home, potentially reducing hospital admissions. Method: Fourteen adult patients with CF scored ease of clearance and breathlessness with ACT before and after addition of NIV to normal ACT routine using a visual analog scale. Patient views on NIV with ACT were collected via a structured interview. Number of home intravenous (IV) antibiotic courses and days in hospital was collected for one year pre-and post-NIV provision. Results: Patients reported statistically significant improvements in ease of clearance (p = 0.011) and reduced breathlessness during ACT using NIV (p = 0.011). Structured interview results indicated patient reports of sputum clearance improved. In-patient days were lower, while home IV days were higher after NIV was set up, although not statistically significant. Conclusion: This study is limited by small numbers; however, trends towards less hospital admissions and greater patient ease while using NIV with ACT warrant further investigation.
机译：背景：关于囊性纤维化（CF）人群中无创通气（NIV）和气道清除技术（ACT）的使用频率，目前尚无公开文献。据报告，英国超过16岁的CF人口中有3.9％（191人，注册5062人）使用NIV。但是，未指定这是用于ACT还是呼吸衰竭。将NIV与ACT一起使用可减少CF患者住院期间的呼吸和疲劳工作。我们假设这些效应可以在家中复制，可能减少住院人数。方法：使用视觉模拟量表，在将NIV加入正常ACT常规前后，对14名成年CF患者进行ACT清除和呼吸困难的评分。通过结构化访谈收集了患者对ACT的NIV的看法。在提供NIV之前和之后的一年中，收集了家庭静脉注射（IV）抗生素疗程和住院天数。结果：患者报告在使用NIV的ACT期间，清除的便利性显着改善（p = 0.011）和呼吸困难减少（p = 0.011）。结构化的访谈结果表明，患者对痰清除率的报告有所改善。 NIV建立后，住院天数减少，而家庭IV天数增加​​，尽管无统计学意义。结论：这项研究受到少数人的限制。但是，将NIV与ACT结合使用时，医院住院人数减少和患者放宽的趋势值得进一步研究。

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